University of California, Berkeley scientists have for the first time used CRISPR-Cas9 gene editing to disable a defective gene that causes amyotrophic lateral sclerosis, or Lou Gehrig's disease, in mice, extending their ...
Dec 20, 2017
0
1079
For a drug to be effective and not harmful it needs to be administered at the right dosage. Certain enzymes in the body eliminate drugs, and the activity of these enzymes vary between individuals. Researchers at the Max Planck ...
Jul 8, 2022
0
86
Proteins commonly known as BRCA—short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development. If the ...
Jun 12, 2018
0
991
When the spinal cords of mice and humans are partially damaged, the initial paralysis is followed by the extensive, spontaneous recovery of motor function. However, after a complete spinal cord injury, this natural repair ...
Sep 21, 2023
0
366
Genes known to be essential to life—the ones humans need to survive and thrive in the womb—also play a critical role in the development of autism spectrum disorder (ASD), suggests a new study from Penn Medicine geneticists ...
Dec 12, 2016
0
1112
The first attempt in the United States to use a gene editing tool called CRISPR against cancer seems safe in the three patients who have had it so far, but it's too soon to know if it will improve survival, doctors reported ...
Nov 6, 2019
0
4733
Scientists at the University of Maryland have developed a new, web-based tool that enables researchers to quickly and easily visualize and compare large amounts of genomic information resulting from high-throughput sequencing ...
Aug 3, 2014
0
0
A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, ...
Sep 20, 2022
0
893
Stem cell transplants do not lead to changes in the DNA of the donor cells. That's according to a new study, which provides important evidence for the safety of this procedure. The researchers also found clues that an anti-virus ...
Sep 7, 2021
0
149
The world of epigenetics—where molecular 'switches' attached to DNA turn genes on and off—has just got bigger with the discovery by a team of scientists from the University of Cambridge of a new type of epigenetic modification.
Dec 21, 2015
4
2153
