mBio

Diseases, Conditions, Syndromes

Zika outbreak may be coming to an end

Scientists have measured the Zika burden in a Brazilian metropolis, and their data indicate that the outbreak may be coming to an end and further outbreaks in the region seem unlikely. The study has also provided new evidence ...

Diseases, Conditions, Syndromes

Researchers help develop new antifungal drug

University of Liverpool researchers, working with F2G Limited (Eccles, Manchester), have developed a new antifungal drug to help in the treatment of life threatening invasive fungal infections such as invasive aspergillosis.

Diseases, Conditions, Syndromes

Researchers identify novel way to target Ebola

Researchers have identified a potential new way to attack Ebola. Scientists have discovered that a protein called Tim-1 (T-cell immunoglobulin and mucin domain-containing protein 1) plays a key role in the development of ...

Genetics

Household environment—not genetics—shapes salivary microbes

Researchers in the United Kingdom have discovered that the mix of microorganisms that inhabit a person's saliva are largely determined by the human host's household. The study, published this week in mBio, an open-access ...

Immunology

New receptor found on scavenger cells

Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people. If a patient is infected with the virus and gets a bacterial infection on top of it, it can lead ...

Diseases, Conditions, Syndromes

Scientists develop infection model for tickborne flaviviruses

National Institutes of Health (NIH) scientists have filled a research gap by developing a laboratory model to study ticks that transmit flaviviruses, such as Powassan virus. Powassan virus was implicated in the death of a ...

Diseases, Conditions, Syndromes

Once invincible superbug squashed by 'superteam' of antibiotics

The golden age of antibiotics may be drawing to a close. The recent discovery of E. coli carrying mcr-1 and ndm-5—genes that make the bacterium immune to last-resort antibiotics—has left clinicians without an effective ...

Diseases, Conditions, Syndromes

Epigenetic drugs show promise as antivirals

Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a study reported in a recent issue of the journal mBio. The study demonstrated that histone methyltransferases EZH2/1 ...

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