MeSH tree: D12.776.705
Parkinson's disease (PD), as well as many other neurodegenerative disorders, has shown a link between the abnormal aggregation of a protein called α-synuclein (aSyn) and neuronal death. These aggregates, known as Lewy bodies ...
Jul 25, 2024
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60
A new preclinical model offers a unique platform for studying the Parkinson's disease process and suggests a relatively easy method for detecting the disease in people, according to a new study led by Weill Cornell Medicine ...
Jul 23, 2024
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78
To date, Parkinson's disease (PD) is diagnosed clinically and rather late in the course of the disease. There is an urgent need to find an objective, quantifiable biomarker for the diagnosis of this highly prevalent movement ...
Jul 22, 2024
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40
Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...
Jul 15, 2024
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56
A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken & Ruth Davee Department of Neurology's Division of Movement Disorders, have uncovered previously unknown cellular mechanisms involved ...
Jul 1, 2024
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68
The structural and functional organization of the brain as shown on MRI can predict the progression of brain atrophy in patients with early-stage, mild Parkinson's disease, according to a study published today in Radiology, ...
Jun 25, 2024
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In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing ...
Jun 17, 2024
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69
In a study published in Neuron, researchers have identified four new genetic risk factors for multiple system atrophy (MSA), shedding light on this poorly understood disorder. The study, which involved collaboration from ...
May 8, 2024
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58
Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments.
Apr 17, 2024
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89
The nose or the gut? For the past two decades, the scientific community has debated the wellspring of the toxic proteins at the source of Parkinson's disease. In 2003, a German pathologist, Heiko Braak, MD, first proposed ...
Apr 11, 2024
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