MeSH tree: C16.320.070
Researchers from multiple institutions in China have found a way to use gene editing to reactivate dormant fetal oxygen-transporting proteins in adult blood cells to potentially reverse a wide range of blood disorders.
5.2% of the global population carry hemoglobin abnormalities, resulting in 300,000 to 400,000 children born with severe hemoglobinopathies annually. Thalassemia, a hereditary hemoglobinopathy, occurs in 4.4 out of every 10,000 ...
Nov 17, 2023
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Medical research has shown promising results regarding the potential of gene therapy to cure genetic conditions such as sickle cell disease and the findings of this study, published in Nature Medicine, offer important new ...
Nov 16, 2023
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Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in the U.K.
Nov 16, 2023
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A clinical trial by Menzies School of Health Research (Menzies) published in The Lancet has revealed promising results to reduce malaria relapses, through the broader use of primaquine.
Nov 16, 2023
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A team at Weill Cornell Medicine has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new ...
Nov 14, 2023
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For pediatric patients with sickle cell disease (SCD), ophthalmologic complications include nonproliferative retinopathy (NPR) and proliferative retinopathy (PR), which occur in 33 and 6 percent, respectively, according to ...
Nov 9, 2023
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500,000 children are born with hemoglobinopathies annually, and 80% of them are born in developing countries. According to the Global Prevention and Control of Hemoglobinopathies report, carrier screening could potentially ...
Nov 8, 2023
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Children and young adults with kidney failure due to sickle cell disease (SCD) wait longer for a kidney transplant and have significantly higher mortality when compared to children and young adults with kidney failure not ...
Nov 6, 2023
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A new gene therapy for sickle cell disease has been deemed safe by a U.S. Food and Drug Administration advisory panel, paving the way for full approval by early December 2023.
Nov 2, 2023
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