Evaluation of ruxolitinib, a JAK inhibitor, in multiple myeloma
A new research perspective titled "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma" has been published in Oncotarget.
Feb 7, 2024
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Enzymes and Coenzymes: News and Research on Protein-Tyrosine Kinases
MeSH tree: D08.811.913.696.620.682.725
Advancing the generation of in-vivo chimeric lungs in mice using rat-derived stem cells
Chronic obstructive pulmonary disease (COPD) is the third-leading cause of death worldwide. It is marked by lung damage that is lasting and incurable, leaving lung transplantation as the only viable treatment option. Unfortunately, ...
Jan 5, 2024
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Organoids study discovers promising treatment for deadly uterine cancer
QUT scientists have discovered a promising new therapy for a deadly type of endometrial cancer that has a poor prognosis if the cancer spreads or returns after initial treatment, a plight that affects 15%–20% of endometrial ...
Dec 13, 2023
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New cause of diabetes discovered, offering potential target for new classes of drugs to treat the disease
Researchers at Case Western Reserve University and University Hospitals have identified an enzyme that blocks insulin produced in the body—a discovery that could provide a new target to treat diabetes.
Dec 8, 2023
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The first oncogene was found more than 40 years ago: Research discovers it has a previously unknown mechanism of action
In the late 1970s, the relationship between the c-Src gene and cancer was discovered. The first oncogene was identified. Since then, c-Src has been found to be overactivated in half of colon, liver, lung, breast, prostate ...
Oct 31, 2023
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Study directly links high insulin levels to pancreatic cancer
A new study from researchers at the University of British Columbia's Faculty of Medicine reveals a direct link between high insulin levels, common among patients with obesity and type 2 diabetes, and pancreatic cancer.
Oct 31, 2023
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Research links single gene to female infertility
Loss of a single gene could be enough to cause female infertility, with research identifying that women won't make eggs without the protein it produces.
Oct 25, 2023
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Trial finds adding immune modulator to targeted therapy does not improve survival in difficult-to-treat thyroid cancer
Results of a multicenter phase II clinical trial led by the University of Chicago Medicine Comprehensive Cancer Center show that adding an immunomodulatory agent to treatment with the targeted tyrosine kinase inhibitor (TKI) ...
Sep 1, 2023
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Patients with refractory metastatic colorectal cancer experience survival benefits with fruquintinib
Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in ...
Jun 16, 2023
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Scientists find treatment for rare genetic skin disorder
Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential ...
May 31, 2023
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