MeSH tree: C10.228.140.079.545
Huntington's disease is a genetically-based neurodegenerative disorder that causes motor, cognitive and psychiatric disorders in the affected individuals. Understanding the alterations in the neural circuits in this disorder ...
Jun 7, 2023
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89
The drug valbenazine statistically improves chorea, a movement disorder commonly associated with Huntington's disease, when compared to a placebo, according to a recent international study led by UTHealth Houston researcher ...
May 19, 2023
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72
When we think of boxing, it's understandable many of us wouldn't associate it with being 'good' for our brains. However, new Edith Cowan University (ECU) research undertaken in partnership with The Perron Institute and boxer ...
May 3, 2023
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42
Cambridge scientists have shown how the brain's ability to clear out toxic proteins is impaired in Huntington's disease and other forms of dementia—and how, in a study in mice, a repurposed HIV drug was able to restore this ...
Apr 26, 2023
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71
A team with the participation of researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) has revealed the structure of the protein responsible for Huntington's ...
Apr 20, 2023
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71
Magnetic resonance imaging (MRI) is how we visualize soft, watery tissue that is hard to image with X-rays. But while an MRI provides good enough resolution to spot a brain tumor, it needs to be a lot sharper to visualize ...
Apr 17, 2023
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Investigators led by D. James Surmeier, Ph.D., the Nathan Smith Davis Professor and chair of Neuroscience, have uncovered previously unknown neuronal circuits that contribute to brain dysfunction in Huntington's disease.
Apr 17, 2023
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75
Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging. In recent years, studies on different model organisms have already shown ...
Apr 3, 2023
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344
In patients with Huntington's disease, neurons in a part of the brain called the striatum are among the hardest-hit. Degeneration of these neurons contributes to patients' loss of motor control, which is one of the major ...
Jan 20, 2023
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54
A research team led by the University of California, Irvine has linked the mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells that are caused by changes in metabolism. ...
Dec 21, 2022
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