CAR-T cell researchers optimistic about future of treating blood cancers
Survival outcomes using chimeric antigen receptor-T cell therapy (CAR-T cell therapy) continue to be impressive for patients with some blood cancers.
Sep 15, 2023
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Pathological Conditions, Signs and Symptoms: News and Research on Cytokine Release Syndrome
MeSH tree: C23.550.470.790.250
New technique helps CAR T therapies fight cancer cells while minimizing severe side effects
In recent years, cancer researchers have hailed the arrival of chimeric antigen receptor T cell (CAR T) therapy, which has delivered promising results, transforming the fight against various forms of cancer. The process involves ...
Sep 13, 2023
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New hope for inflammatory disorders: Controlling dangerous immune response
The inflammatory response is indispensable for protective immunity, yet microbial pathogens often trigger an excessive response, a "cytokine storm," harmful to the host. Despite recent advances in our understanding of inflammatory ...
Jul 19, 2023
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Immunotherapy improves remission for relapsed, refractory leukemia: Clinical trial
A single infusion of chimeric antigen receptor T-cell (CAR-T) therapy induced complete response or remission in patients with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), ...
Jul 14, 2023
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Apple-shaped obesity is associated with cytokine storm and a higher risk of death in COVID-19 patients
Eating an apple a day may keep the doctor away, but having an apple shape is not nearly as healthy. Now, researchers from Japan have shown that people who carry their weight in their bellies may be at greater risk of poor ...
Jun 20, 2023
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Scientists discover pathogenic mechanism and novel treatment for Klebsiella pneumoniae
Two novel approaches for the treatment of infections caused by antibiotic-resistant superbugs have shown efficacy and good clinical application potential in studies performed by a team from The Hong Kong Polytechnic University ...
Jun 20, 2023
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New study gives clues on why exercise helps with inflammation
Researchers have long known that moderate exercise has a beneficial impact on the body's response to inflammation, but what's been less understood is why. New research coming out of York University done on a mouse model suggests ...
Jun 15, 2023
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Treatment found to reduce progression of rare blood cancer by 74%
A treatment that involves genetically modifying the body's own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type of blood cancer, results showed Monday.
Jun 5, 2023
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Axi-cel significantly improves survival in trial patients with early relapsed or refractory large B-cell lymphoma
Patients with early relapsed or refractory large B-cell lymphoma had significantly improved overall survival when treated with the chimeric antigen receptor (CAR) T cell therapy axicabtagene ciloleucel (axi-cel) when compared ...
Jun 5, 2023
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Epkinly granted accelerated FDA approval for lymphoma treatment
The U.S. Food and Drug Administration has granted accelerated approval for Genmab's Epkinly (epcoritamab-bysp) for relapsed or refractory diffuse large B-cell lymphoma (DLBCL), including DLBCL arising from indolent lymphoma, ...
May 23, 2023
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