MeSH tree: B04.280.650.160.650.900
Vaccines that prevent smallpox and mpox come in two varieties. One uses a single shot of a live virus but carries the risk of serious side effects; the other, which is newer and made with replication deficient virus, has ...
Nov 13, 2024
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Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics. For example, the strain called MVA (modified vaccinia Ankara), which is unable to replicate in ...
May 22, 2024
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Northwestern Medicine investigators led by Derek Walsh, Ph.D., professor of Microbiology-Immunology, have discovered how poxviruses disarm and evade mitochondrial-driven antiviral responses for their replication in host cells, ...
Dec 19, 2023
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Equipping cancer-infecting (oncolytic) viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study in ...
Aug 14, 2023
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A team of researchers from the Chinese Academy of Sciences, the Chinese Academy of Agricultural Sciences, and Beijing Institute of Pharmacology and Toxicology have made significant progress in developing multi-valent mRNA ...
Jun 21, 2023
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Combining a cancer-targeting virus with radiation to treat brain cancer in mice was more effective than either therapy on its own according to new research, providing hope for new treatments that combine immunotherapy with ...
Jun 14, 2023
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Folks of a certain vintage have the tell-tale crater on their upper arms: The discolored, shallow scars from the smallpox vaccine.
Aug 18, 2022
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Pox viruses are able to get a head start on infecting a host by delivering a package of proteins that directly interferes with the body's innate immune system.
Jul 14, 2022
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