Higher pulse wave velocity seen in well-controlled diabetes

November 10, 2012
Higher pulse wave velocity seen in well-controlled diabetes
Pulse wave velocity is higher among patients with well-controlled type 2 diabetes when compared to controls, and is associated with white matter lesions, according to a study published online Nov. 5 in Diabetes Care.

(HealthDay)—Pulse wave velocity is higher among patients with well-controlled type 2 diabetes when compared to controls, and is associated with white matter lesions, according to a study published online Nov. 5 in Diabetes Care.

Esben Laugesen, M.D., from Aarhus University Hospital in Noerrebrogade, Denmark, and colleagues measured arterial stiffness with carotid-femoral pulse wave velocity and cerebral white matter lesions by (qualitatively graded by the Breteler scale) in 89 patients diagnosed with type 2 diabetes in the past five years and 89 matched controls. The authors note that arterial stiffness is associated with cardiovascular events and white matter lesions are associated with stroke.

The researchers found that the diabetes group had excellent glycemic control and had and lower total cholesterol than controls. However, even after adjusting for confounding variables, including age, sex, diabetes, , 24-hour mean arterial blood pressure, and medications, they had significantly higher carotid-femoral pulse wave velocity, which was significantly associated with Breteler score and cerebral white matter lesion volume.

"Pulse wave velocity was higher among patients with well-controlled type 2 diabetes compared with controls and was independently associated with white matter lesions," Laugesen and colleagues conclude. "Pulsed wave velocity may represent a clinically relevant parameter in the evaluation of cerebrovascular disease risk in type 2 diabetes."

The study was partially funded by research grants from the Foundation.

Explore further: Arterial stiffness inversely tied to plasma adiponectin levels

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Arterial stiffness inversely tied to plasma adiponectin levels

September 27, 2012
(HealthDay)—Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

Metabolic syndrome linked to arterial stiffness in CKD

June 4, 2012
(HealthDay) -- For patients with chronic kidney disease (CKD), those with metabolic syndrome (MetS) have increased arterial stiffness but no increase in endothelial dysfunction, compared to those without MetS, according to ...

A novel method for simultaneously measuring blood pressure and arterial stiffness

February 10, 2012
Arterial stiffness due to is a major contributor to cardiovascular disease but is very difficult to measure. It also can influence blood pressure readings since these rely on the time taken for arteries to return to normal ...

White matter structural changes ID'd in children with T1DM

September 17, 2012
(HealthDay)—Children with type 1 diabetes have significant structural differences in the white matter of their brain compared to healthy children, which correlates with hemoglobin A1c (HbA1c) values, according to a study ...

Study finds relationship between dairy food intake and arterial stiffness

June 7, 2012
(Medical Xpress) -- Adults who include dairy foods in their diets might be reducing their arterial stiffness and decreasing their risk of cardiovascular disease, according to a new study by researchers from the University ...

Subclinical atherosclerosis noted in diffuse scleroderma

August 29, 2012
(HealthDay)—Patients with diffuse systemic sclerosis (SSc), without any clinical evidence of cardiovascular disease, have indicators of subclinical atherosclerosis, according to a study published online Aug. 16 in Arthritis ...

Recommended for you

Diabetes can be tracked with our Google searches

July 26, 2017
The emergence of Type 2 Diabetes could be more effectively monitored using our Google searches—helping public health officials keep track of the disease and halt its spread—according to research by the University of Warwick.

Scientists discover a new way to treat type 2 diabetes

July 21, 2017
Medication currently being used to treat obesity is also proving to have significant health benefits for patients with type 2 diabetes. A new study published today in Molecular Metabolism explains how this therapeutic benefit ...

Alzheimer's drug cuts hallmark inflammation related to metabolic syndrome by 25 percent

July 20, 2017
An existing Alzheimer's medication slashes inflammation and insulin resistance in patients with metabolic syndrome, a potential therapeutic intervention for a highly dangerous condition affecting 30 percent of adults in the ...

Diabetes or its precursor affects 100 million Americans

July 19, 2017
Almost one-third of the US population—100 million people—either has diabetes or its precursor condition, known as pre-diabetes, said a government report Tuesday.

One virus may protect against type 1 diabetes, others may increase risk

July 11, 2017
Doctors can't predict who will develop type 1 diabetes, a chronic autoimmune disease in which the immune system destroys the cells needed to control blood-sugar levels, requiring daily insulin injections and continual monitoring.

Diabetes complications are a risk factor for repeat hospitalizations, study shows

July 7, 2017
For patients with diabetes, one reason for hospitalization and unplanned hospital readmission is severe dysglycemia (uncontrolled hyperglycemia - high blood sugar, or hypoglycemia - low blood sugar), says new research published ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.