Global burden of disease study focuses on liver cancer

October 5, 2017, The JAMA Network Journals

A new article published by JAMA Oncology reports the results of the Global Burden of Disease 2015 study on primary liver cancer incidence, death and years of healthy life lost in 195 countries or territories from 1990 to 2015.

Liver cancer is among the leading causes of cancer death worldwide.

The article by the Global Burden of Disease Liver Cancer Collaboration and corresponding author Christina Fitzmaurice, M.D., M.P.H., of the University of Washington, Seattle, estimates there were 854,000 new cases of liver cancer and 810,000 deaths globally in 2015.

Cases of incident (new) liver cancer increased 75 percent between 1990 and 2015, which was mostly explained by population aging and , according to the authors.

In 2015, hepatitis B virus was the leading cause of new cases of liver cancer, deaths and disability-adjusted life-years (DALYS), which is the sum of years of life lost and years lived with disability such that one DALY can be interpreted as one lost year of . Alcohol was the next leading cause, according to the results.

East Asia had the most new cases of liver cancer, deaths and DALYS, the article reports.

Limitations of the study include that estimates depend on the quality and quantity of data used.

"Liver cancer remains a major public health burden globally. The major causes for are highly preventable or treatable," the article concludes.

Explore further: Study estimates global cancer cases, deaths in 2015

More information: JAMA Oncology (2017). jamanetwork.com/journals/jamao … /jamaoncol.2017.3055

Related Stories

Study estimates global cancer cases, deaths in 2015

December 3, 2016
In 2015, there were an estimated 17.5 million cancer cases around the globe and 8.7 million deaths, according to a new report from the Global Burden of Disease Cancer Collaboration published online by JAMA Oncology.

Estimating the global burden of cancer in 2013; 14.9 million new cases worldwide

May 28, 2015
Researchers from around the world have worked together to try to measure the global burden of cancer and they estimate there were 14.9 million new cases of cancer, 8.2 million deaths and 196.3 million years of a healthy life ...

U.S. liver cancer deaths have doubled since 1980s: study

June 7, 2017
(HealthDay)—Liver cancer is the fastest-growing cause of cancer deaths in the United States, a new study reports.

Cancer's deadly toll grows in less developed countries as new cases increase globally

December 6, 2016
While cancer is the world's second leading cause of death after cardiovascular diseases, the chances of getting cancer and dying from it look radically different depending on where you live, according to a new analysis of ...

Many cancers with largest impact on years of life lost linked to tobacco and alcohol

October 18, 2016
A new study finds eleven of the 15 cancers with the most impact on healthy years of life lost in the United States are closely-associated with two preventable risk factors: smoking and alcohol. The study, appearing early ...

Risk of liver cancer from hepatitis B persists even after clearing the virus

April 22, 2016
Long-term infection with hepatitis B virus (HBV) can cause liver inflammation and increase the risk of liver cancer. Researchers from the US Centers for Disease Control and Prevention, however, found that resolving HBV infection ...

Recommended for you

Study tracks evolutionary transition to destructive cancer

February 23, 2018
Evolution describes how all living forms cope with challenges in their environment, as they struggle to persevere against formidable odds. Mutation and selective pressure—cornerstones of Darwin's theory—are the means ...

Researchers use a molecular Trojan horse to deliver chemotherapeutic drug to cancer cells

February 23, 2018
A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

Lab-grown 'mini tumours' could personalise cancer treatment

February 23, 2018
Testing cancer drugs on miniature replicas of a patient's tumour could help doctors tailor treatment, according to new research.

An under-the-radar immune cell shows potential in fight against cancer

February 23, 2018
One of the rarest of immune cells, unknown to scientists a decade ago, might prove to be a potent weapon in stopping cancer from spreading in the body, according to new research from the University of British Columbia.

Putting black skin cancer to sleep—for good

February 22, 2018
An international research team has succeeded in stopping the growth of malignant melanoma by reactivating a protective mechanism that prevents tumor cells from dividing. The team used chemical agents to block the enzymes ...

Cancer risk associated with key epigenetic changes occurring through normal aging process

February 22, 2018
Some scientists have hypothesized that tumor-promoting changes in cells during cancer development—particularly an epigenetic change involving DNA methylation—arise from rogue cells escaping a natural cell deterioration ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.