Prostate cancer drug given initial 'no' for NHS in England

Prostate cancer drug given initial ‘no’ for NHS in England
Credit: Cancer Research UK

A prostate cancer drug has been provisionally rejected as a first-line treatment on the NHS in England.

The draft recommendation from the National Institute for Health and Care Excellence (NICE) means abiraterone (Zytiga) won't be made routinely available for men with newly diagnosed that has spread to other parts of the body.

As it stands, the NHS in England can only prescribe abiraterone for these men once standard hormone treatment or chemotherapy has failed.

Results from recent clinical trials have shown that giving abiraterone alongside steroids and as a first-line treatment can reduce the chance of the cancer coming back and improve survival compared to hormone therapy alone.

Sir Harpal Kumar, Cancer Research UK's chief executive, called the decision "disappointing". "Two published last year provided compelling evidence of the huge potential benefit of abiraterone for these patients," he said.

What does the decision mean?

NICE published its draft recommendation this week, rejecting abiraterone as a first-line therapy. The committee concluded they couldn't accurately estimate the drug's cost effectiveness based on the data submitted.

The drug's manufacturer, Janssen, can now submit additional data, which will be reviewed later this summer before a final decision is reached.

A NICE spokesperson told The Telegraph : "We understand that some men with prostate will be disappointed by today's news.

"However, we can only recommend drugs that are clinically effective and show value for money compared to current treatment options. In this case, has fallen short."

Kumar urged NICE and Janssen to work together quickly to provide the information that will allow the drug to be recommended.

Explore further

Adding abiraterone to standard treatment improves prostate cancer survival by 40 percent

Provided by Cancer Research UK
Citation: Prostate cancer drug given initial 'no' for NHS in England (2018, June 8) retrieved 30 July 2021 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments