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Medications
Semaglutide effectively treats liver disease in two thirds of patients, research finds
Results from the ESSENCE Phase III clinical trial published in the New England Journal of Medicine show treating patients with semaglutide can halt and even reverse liver disease.
11 hours ago
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Diseases, Conditions, Syndromes
Home washing machines fail to remove important pathogens from textiles
Health care workers who wash their uniforms at home may be unknowingly contributing to the spread of antibiotic-resistant infections in hospitals, according to a new study led by Katie Laird of De Montfort University, published ...
13 hours ago
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Medical research news
Investigational test detects earliest stages of autoimmune assault that causes type 1 diabetes, scientists report
An investigational blood test for type 1 diabetes can accurately detect the disorder's characteristic autoimmunity with only small samples of blood, a feature that makes it ideal to screen pediatric patients, scientists in ...
Investigational gene therapy gives children with rare immune disorder a new lease on life
An investigational gene therapy has successfully restored immune function in all nine children treated with the rare and life-threatening immune disorder called severe leukocyte adhesion deficiency-I, or LAD-I, in an international ...
11 hours ago
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Discovery that microglia can be effectively replaced could transform cell therapy for brain diseases
An international research team led by Professor Kiavash Movahedi from the Brussels Center for Immunology at the Vrije Universiteit Brussel has published unexpected results in the journal Immunity. Their study sheds new light ...
12 hours ago
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Parallel activity in orbitofrontal cortex and hippocampus shapes cognitive maps and schemas, study suggests
As humans and other animals navigate their surroundings and experience different things, their brain creates so-called cognitive maps, which are internal representations of environments or tasks. These mental maps are eventually ...
Depression and other mental health conditions linked to immune response, study finds
Depression, schizophrenia and other mental health conditions affect 1 in 4 people in their lifetime, but the mechanisms underlying these conditions are poorly understood. New research led by researchers at the University ...
13 hours ago
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New 'hidden in plain sight' facial and eye biomarkers for tinnitus severity could unlock path to testing treatments
Researchers at Mass General Brigham have identified new biomarkers for tinnitus by measuring pupil dilation and subtle facial movements that correlate with the level of distress caused by the disorder. Published in Science ...
13 hours ago
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Mechanism behind Parkinson's-like side effects of antipsychotic drugs revealed
A new Northwestern Medicine study has identified the molecular mechanisms that cause a commonly prescribed antipsychotic drug to produce harmful side effects similar to Parkinson's disease symptoms, according to findings ...
13 hours ago
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Live human brain tissue reveals how Alzheimer's-linked protein damages connections
Scientists using living human brain tissue have shown for the first time how a toxic form of a protein linked to Alzheimer's can stick to and damage the connections between brain cells.
13 hours ago
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Experiment sheds new light on the origins of consciousness
An experiment seven years in the making has uncovered new insights into the nature of consciousness and challenges two prominent, competing scientific theories: Integrated Information Theory (IIT) and Global Neuronal Workspace ...
17 hours ago
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Long COVID biomarkers found in blood associated with respiratory problems
Researchers at Karolinska Institutet have identified biomarkers in the blood associated with symptoms of long COVID, particularly severe respiratory disorders. The discovery could pave the way for future diagnosis and treatment. ...
14 hours ago
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Genetic characteristics linked to long-term HIV remission after stopping treatment
Tackling HIV continues to be a major public health challenge, mainly because the persistence of viral reservoirs means that people living with HIV need to take lifelong antiretroviral treatment. But some individuals, known ...
14 hours ago
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Conservatives may self-rate as having better 'mental health' because of stigma around the term, study suggests
Conservatives may rate their mental health more positively than liberals, in part because of the stigma around the phrase "mental health," according to a study published in the open-access journal PLOS One by Brian F. Schaffner ...
14 hours ago
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3D mouse brain atlas promises to accelerate studies of neurological disorders
A new "atlas" developed by researchers at Duke University School of Medicine, University of Tennessee Health Science Center, and the University of Pittsburgh will increase precision in measuring changes in brain structure ...
14 hours ago
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Machine learning brings new insights to astrocytes' role in heroin addiction and relapse
Object recognition software is used by law enforcement to help identify suspects, by self-driving cars to navigate roadways and by many consumers to unlock their cell phones or pay for their morning coffee.
14 hours ago
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Ayahuasca's longer-term psychological effects may be shaped by setting, acute reaction and mental health history
Mounting evidence supports ayahuasca's potential to improve mental health, but its long-term effects are shaped by both individual mental health history and the context in which the psychedelic is used, according to a study ...
14 hours ago
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Compromised synapse-clearing ability linked to autism
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests.
14 hours ago
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National-level actions found to be effective at tackling antibiotic resistance
National-level policies can reduce the impact of antibiotic resistance across diverse countries, according to a study published in the open-access journal PLOS Global Public Health by Peter Søgaard Jørgensen from Stockholm ...
14 hours ago
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Seasonal gene expression affects drug effectiveness and metabolism in primates, study shows
Nagoya University researchers in Japan have found that drug effectiveness, alcohol tolerance, and carbohydrate metabolism change with the seasons. Their findings are based on a comprehensive seasonal gene expression map, ...
14 hours ago
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