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Common arthritis pill repurposed to boost hair regrowth in alopecia patients

Upadacitinib is a medication widely used for the treatment of rheumatoid arthritis that works by inhibiting Janus kinase (JAK) enzymes, which are involved in signaling pathways that regulate immune responses. Now, scientists ...

Experimental pill targets nerve pain pathway, cutting opioid use after abdominal surgery

Opioids can be highly effective at relieving moderate to severe pain, whether it comes from surgery, an injury or conditions such as cancer. They work by activating opioid receptors in the brain and body, which block pain ...

Medical research news

Laser therapy offers weapon against deadly brain tumors

For patients facing a diagnosis of glioblastoma—one of the most aggressive and devastating forms of brain cancer—the standard path forward has long meant invasive open-skull surgery and a daunting prognosis.

Flexible brain circuits can switch between different tasks

As we move through everyday life, our brains engage in a huge variety of cognitive tasks. For example, during a grocery run, we might have to recall the items for a recipe, remember where the clerk said the flour was located ...

Rare gene variants may multiply Alzheimer's disease risk

Alzheimer's disease is the most common form of dementia worldwide, and its development is influenced by a combination of genetic and environmental factors. In recent years, the PLCG2 gene and its encoded enzyme, PLCγ2, have ...

Video games built for prevention can reduce teen depression

Few parents or teachers are likely to suggest that teenagers could benefit from playing more video games. But a new study suggests that a growing class of educational games may be a highly effective tool for treating and ...

ULTRA maps glioma margins in 3D within 30 minutes

One of the major challenges in glioma surgery is that tumor boundaries are often difficult to define. Diffuse gliomas can infiltrate surrounding brain tissue beyond what surgeons can see directly or what conventional imaging ...

Researchers discover immune 'off switch' used by cancer cells

Mayo Clinic researchers have identified a protein that cancer cells use to shut down the body's immune response, a discovery that could help scientists develop new treatments that make cancer immunotherapies more effective.

What's in kratom products? Tests find 85% conflict with labels

What's listed on a kratom product label may not tell the full story. Researchers in the University of Florida College of Pharmacy have found that commercially available kratom products, including many kratom-derived products, ...

Why a UTI hurts—and why that might be a good thing

Australian researchers have discovered a previously overlooked group of bladder nerves that help detect urinary tract infections (UTIs) and trigger the body's response to clear them, providing a potential new target for future ...