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Common arthritis pill repurposed to boost hair regrowth in alopecia patients

Upadacitinib is a medication widely used for the treatment of rheumatoid arthritis that works by inhibiting Janus kinase (JAK) enzymes, which are involved in signaling pathways that regulate immune responses. Now, scientists ...

Experimental pill targets nerve pain pathway, cutting opioid use after abdominal surgery

Opioids can be highly effective at relieving moderate to severe pain, whether it comes from surgery, an injury or conditions such as cancer. They work by activating opioid receptors in the brain and body, which block pain ...

Medical research news

Laser therapy offers weapon against deadly brain tumors

For patients facing a diagnosis of glioblastoma—one of the most aggressive and devastating forms of brain cancer—the standard path forward has long meant invasive open-skull surgery and a daunting prognosis.

Flexible brain circuits can switch between different tasks

As we move through everyday life, our brains engage in a huge variety of cognitive tasks. For example, during a grocery run, we might have to recall the items for a recipe, remember where the clerk said the flour was located ...

Rare gene variants may multiply Alzheimer's disease risk

Alzheimer's disease is the most common form of dementia worldwide, and its development is influenced by a combination of genetic and environmental factors. In recent years, the PLCG2 gene and its encoded enzyme, PLCγ2, have ...

Video games built for prevention can reduce teen depression

Few parents or teachers are likely to suggest that teenagers could benefit from playing more video games. But a new study suggests that a growing class of educational games may be a highly effective tool for treating and ...

ULTRA maps glioma margins in 3D within 30 minutes

One of the major challenges in glioma surgery is that tumor boundaries are often difficult to define. Diffuse gliomas can infiltrate surrounding brain tissue beyond what surgeons can see directly or what conventional imaging ...

Has the definition of autism become too broad to be useful?

The definition of autism may have become so broad that it risks confusion and even misdiagnosis, according to a new editorial by UCL professor Dame Uta Frith, whose pioneering research in the 1960s and '70s laid the foundations ...

Brain activity reveals the melodies that people imagine

In a study led by Jii Kwon and Chun Kee Chung of Seoul National University, researchers explored whether they could recreate melodies from the brain activity of people who imagined how songs continue after listening to a ...

Parkinson's gene linked to early dysfunction in brain cells

Northwestern Medicine scientists have uncovered how a major Parkinson's disease gene disrupts the brain's most vulnerable dopamine-producing neurons before detectable neuronal loss. The study offers new clues for developing ...

Blood marker tracks hidden progression in multiple sclerosis

Modern therapies have transformed care for people with multiple sclerosis (MS). Yet the disease continues to progress in a substantial proportion of patients, even in the absence of relapses. Detecting and treating this gradual ...