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Neuroscience
Combining cell therapy with approved drug shows promise for treating multiple sclerosis
Multiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer around nerve cells, known as the myelin sheath. This leads to nerve damage and worsening disability. Current treatments, ...
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Genetics
Study reveals key role of TRIO gene in epileptic encephalopathies
What are the molecular and cellular mechanisms by which some babies develop epileptic encephalopathies and autism spectrum disorder? That's what researchers in Canada and France set out to uncover—and they think they've ...
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Medical research news
Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer
Final results from the SWOG S1011 randomized Phase III clinical trial, published in the New England Journal of Medicine, indicate patients undergoing surgery for localized muscle-invasive bladder cancer derive no significant ...
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Study reveals molecular mechanism of genetic variant that causes mirror movement disorder
A team of Canadian and American scientists has made a promising breakthrough in understanding the origins of a mysterious neurological disorder known as mirror movements.
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New genetic testing pathways could ensure patients get personalized BRCA-linked cancer treatments
Scientists have developed a new clinical pathway for testing for the cancer-causing faults in the BRCA gene that could ensure patients get the right treatment and boost the number of people who get tested.
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Brain molecule that makes neurons less selective could deepen understanding of human cognition
Neuroscientists from Johns Hopkins Medicine say they have determined how a brain cell surface molecule shapes the way certain neurons behave.
3 hours ago
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Synthetic peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
A peptide synthesized by researchers at the University of São Paulo (USP) in Brazil protected human lung cells against infection by SARS-CoV-2 in the laboratory and eliminated the inflammation caused by the virus in mice ...
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Plant compound used in traditional medicine may help fight tuberculosis
A compound found in African wormwood—a plant used medicinally for thousands of years to treat many types of illness—could be effective against tuberculosis, according to a new study published in the Journal of Ethnopharmacology.
2 hours ago
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Organ allocation changes lead to better survival rates for children with liver failure
Liver transplantation is currently the only cure for pediatric acute liver failure (PALF), a rapidly progressing and life-threatening condition that can affect previously healthy children. Some children do not get a transplant ...
2 hours ago
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Satisfying friendships could be key for young single adults' happiness, research suggests
A new analysis assesses the heterogeneity of factors linked with happiness among single Americans who are just entering adulthood, highlighting a particularly strong link between happiness and satisfying friendships. Lisa ...
4 hours ago
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Researchers discover mechanism by which estrogen can trigger fast neuronal responses
Estrogen, the major female ovarian hormone, can trigger nerve impulses within milliseconds to regulate a variety of physiological processes. At Baylor College of Medicine, Louisiana State University and collaborating institutions, ...
4 hours ago
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Viruses found hiding in lungs' immune cells long after initial illness
Doctors have long known that children who become seriously ill with certain respiratory viruses such as respiratory syncytial virus (RSV) are at elevated risk of developing asthma later in life. What they haven't known is ...
5 hours ago
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Researchers develop insights into KRAS mutations in pancreatic cancers
A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to less invasiveness and ...
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Scientists uncover genetic cause of rare autoimmune disorder
A team of international scientists has uncovered the genetic underpinnings of a rare, inherited autoimmune disorder, according to a study recently published in Science Translational Medicine.
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Curbing blood cancers by teaching immune cells to kill mutant stem cells
Blood stem cells, which give rise to all of our blood cell types, undergo a quality assurance process after they're born. As the lab of Leonard Zon, MD, director of the Stem Cell Research program at Boston Children's, has ...
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Dementia diagnostic markers shown to change with time of day
The time of day when blood is taken can affect the results of tests for diagnosing dementia, according to new research led by the University of Surrey. The study has been published in Translational Psychiatry.
5 hours ago
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Research shows regional differences in medical and psychological harms of obesity
Individuals struggling with obesity face a number of social and health difficulties, but those problems are less severe if they live in areas where obesity is prevalent, a new study suggests.
3 hours ago
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Reducing sitting by about 40 minutes daily may prevent back pain, research suggests
A new study from the University of Turku in Finland showed that reducing daily sitting prevented back pain from worsening over six months. The result strengthens the current understanding of the link between activity and ...
6 hours ago
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Cutting corners results in rare genetic diseases being undiagnosed, say scientists
Inaccurate naming of genetic diseases is resulting in some rare genetic diseases needlessly being undiagnosed, University of Manchester scientists warn. A Nature Genetics communication paper, published today adds to existing ...
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Scientists decode key mutation in many cancers, pointing to expanded role of RNA in human gene expression
Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to cancer. A new study from ...
7 hours ago
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