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Genetics

Largest-ever genetic study of epilepsy finds possible therapeutic targets

The largest and most diverse study to date of epilepsy's genetic factors has revealed new potential targets for treatment, both shared by and unique to different subtypes of epilepsy. The findings point to factors involved ...

Diseases, Conditions, Syndromes

Study demonstrates that mpox vaccine antibody responses wane within a year

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated that mpox antibody levels declined rapidly and nearly returned to baseline six to 12 months after patients received the mpox vaccination. ...

Medical research news

Immunology

Here's why B cells benefit from booster shots

Certain infectious diseases, such as COVID or the flu, evolve constantly, shapeshifting just enough to outmaneuver our immune systems and reinfect us repeatedly. But subsequent reinfections often don't lead to the most severe ...

Diseases, Conditions, Syndromes

How doxycycline for STI prevention affects the gut microbiome

Taking a dose of the oral antibiotic doxycycline after a high-risk sexual encounter has dramatically reduced the incidence of sexually transmitted infections (STIs) in places where the strategy is being tried.

Oncology & Cancer

New imaging technique accurately detects aggressive kidney cancer

A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form ...

Medical research

Study identifies potential novel drug to treat tuberculosis

A new study published in Microbiology Spectrum demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant ...

Ophthalmology

Researchers use AI to help people see more clearly

Myopia, also known as nearsightedness, is on the rise, especially among children. Experts predict that by the year 2050, myopia will affect approximately 50% of the world's population. Researchers believe that an increase ...

Oncology & Cancer

Researchers learn how cancer cells divide despite treatment

Researchers in the lab of Jean Cook, Ph.D., chair and professor in the Department of Biochemistry and Biophysics, have identified the cellular processes that occur when you take a cancer drug meant to stop rapid cell growth ...

Health informatics

Making clinical guidelines work for large language models

Clinical guidelines are essential to the practice of evidence-based medicine, but they are long and complex, which makes it hard for busy doctors to quickly and easily find the information they need to care for each patient.

Obstetrics & gynaecology

Pandemic health behaviors linked to rise in neonatal health issues

Studies show that social distancing and other public health measures during the COVID-19 pandemic effectively reduced the spread of the deadly virus. However, they had unanticipated effects such as reduced health care accessibility ...

Medical research

Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

Genetics

Understanding molecular drivers of lymphedema

Northwestern Medicine scientists have uncovered molecular mechanisms underlying lymphatic valve development, a discovery which could prove useful in treating lymphedema, according to a study published in the Journal of Clinical ...