Friedrich Miescher Institute for Biomedical Research

The Friedrich Miescher Institute for Biomedical Research (FMI) is part of the Novartis Research Foundation and is a world-class center for basic research in life sciences based in Basel, Switzerland. The FMI is devoted to the pursuit of fundamental biomedical research. Areas of expertise are: In these fields the FMI has gained international recognition as a center of excellence in innovative biomedical research. Research is carried out in 22 independent but highly interactive research teams. In addition, seven technology platforms, ranging from functional genomics to microscopy and imaging, support the research activities with cutting-edge technology. As of 2011, the institute counts 320 collaborators of which 90 are postgraduate students participating in the FMI International PhD Program, 100 are postdoctoral collaborators and 22 are research group leaders. Since 2004, the institute is led by Susan M. Gasser. in chronological order The FMI is an affiliated institute of the University of Basel. It provides biomedical research and career training for over 90 PhD students. FMI selects its highly international student body during a twice-yearly interview-based selection program.

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Medical research

Preventing the onset of schizophrenia in a mouse model

Although predisposing processes occur earlier, schizophrenia emerges at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse ...

Psychology & Psychiatry

Stressed, anxious? Ask the brain

Our actions are driven by "internal states" such as anxiety, stress or thirst—which will strongly affect and motivate our behaviors. Not much is known about how such states are represented by complex brain-wide circuits, ...

Genetics

New findings on autism-related disorder

In a study published today in Nature, Marc Bühler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have taken a major step forward in elucidating the mechanisms underlying a disorder known ...

Neuroscience

High-speed locomotion neurons found in the brainstem

Think of taking a casual stroll on a sunny Sunday afternoon or running at full speed to catch a bus for work on Monday morning as two extremes. Both forms of locomotion entail a perfect interplay between arms and legs, yet ...

Neuroscience

Coupling of movement and vision

In a study published in Cell, Georg Keller and his group shed light on neural circuits in the cortex that underlie the integration of movement and visual feedback. They identified a mechanism in the visual cortex responsible ...

Neuroscience

Computations of visual motion in the brain

Botond Roska and his group at the FMI have elucidated how the retina and the visual cortex work together in visual motion perception. They found that cortical cells, which respond preferentially to backward image motion, ...

Genetics

Epigenetic regulation of face formation

Each face is unique, even though the genes controlling facial shape are almost identical in every individual. Filippo Rijli and his team at the Friedrich Miescher Institute for Biomedical Research (FMI) have discovered an ...

Neuroscience

Transcriptional control of sound discrimination

Filippo Rijli and his team at the Friedrich Miescher Institute for Biomedical Research have identified two genes that control sound discrimination in the brain. The Hox2 transcription factors act in the mouse brain stem and ...

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