The brain's emotion-processing center—the amygdala—is one of several brain regions involved in social behavior. But the exact role that this almond-shaped structure plays in the so-called 'social brain' remains mysterious. ...
Mar 4, 2021
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68
In a comprehensive study, researchers from the Rijli group found that a single Hox transcription factor expressed in a group of neurons of the pontine nucleus—the cerebral cortex most important brainstem relay to the cerebellum—determines ...
Jun 22, 2020
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108
Mutations in the nuclear structural protein lamin A produce rare, tissue-specific diseases called laminopathies. To study these diseases, researchers from the Gasser group introduced a mutation inducing a human laminopathy ...
Mar 16, 2020
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23
Although predisposing processes occur earlier, schizophrenia emerges at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse ...
Sep 9, 2019
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80
Our actions are driven by "internal states" such as anxiety, stress or thirst—which will strongly affect and motivate our behaviors. Not much is known about how such states are represented by complex brain-wide circuits, ...
Apr 24, 2019
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58
In a study published today in Nature, Marc Bühler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have taken a major step forward in elucidating the mechanisms underlying a disorder known ...
May 24, 2018
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57
Giovanna Brancati and Helge Grosshans from the FMI have described target specialization of miRNAs of the let-7 family. They identified target site features that determine specificity, and revealed that specificity can be ...
Mar 23, 2018
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27
Think of taking a casual stroll on a sunny Sunday afternoon or running at full speed to catch a bus for work on Monday morning as two extremes. Both forms of locomotion entail a perfect interplay between arms and legs, yet ...
Oct 23, 2017
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34
In a study published in Cell, Georg Keller and his group shed light on neural circuits in the cortex that underlie the integration of movement and visual feedback. They identified a mechanism in the visual cortex responsible ...
Jun 22, 2017
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14
Botond Roska and his group at the FMI have elucidated how the retina and the visual cortex work together in visual motion perception. They found that cortical cells, which respond preferentially to backward image motion, ...
May 22, 2017
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