Sanford Burnham Prebys Medical Discovery Institute

Sanford Burnham Prebys Medical Discovery Institute (SBP) is an non-profit medical research institute with locations in La Jolla, California and Orlando, Florida. There are more than 850 scientists at SBP blending cutting-edge fundamental research with robust drug discovery to address unmet clinical needs in the areas of cancer, neuroscience, immunity, and metabolic disorders.

Website
http://www.sbpdiscovery.org/
Wikipedia
https://en.wikipedia.org/wiki/Sanford_Burnham_Prebys_Medical_Discovery_Institute

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Diseases, Conditions, Syndromes

New stem cell source offers hope to patients with rare liver disease

Researchers from Sanford Burnham Prebys have discovered a new source of stem cells just outside the liver that could help treat people living with Alagille syndrome, a rare, incurable genetic disorder in which the bile ducts ...

Oncology & Cancer

Researchers identify a novel player in acute myeloid leukemia

A new study led by scientists at Sanford Burnham Prebys has shown that the protein RNF5 plays an unusual role in acute myeloid leukemia (AML). Unlike its expected role, marking aberrant proteins for destruction, RNF5 binds ...

Psychology & Psychiatry

Biomarker could help diagnosis schizophrenia at an early age

Scientists at Sanford Burnham Prebys have discovered how levels of a protein could be used in the future as a blood-based diagnostic aid for schizophrenia. The activity of the protein, which is found in both the brain and ...

Diseases, Conditions, Syndromes

Recurrent infections of salmonella can lead to colitis

An international research group, led by Jamey Marth, Ph.D., a professor at Sanford Burnham Prebys, has shown that the Neuraminidase 3 (Neu3) enzyme is responsible for the onset and progression of colitis—a chronic digestive ...

Genetics

COVID-19: Scientists identify human genes that fight infection

Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Knowing which genes help control viral infection can greatly assist researchers' understanding ...

Oncology & Cancer

Starving tumors by blocking glutamine uptake

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake of glutamine, a key food source for many tumors, and slows the growth of melanoma. The drug is a small ...

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