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Silicon exoskeletons for blood cells: Engineered blood cells successfully transfused between species

A study by an international research collaborative reports a stunning blood modification method that not only protects red blood cells for perfusion-based transplant organ cryostorage, but could make blood types cross-compatible ...

Medical research

Scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects

To the known risk factors for cardiovascular disease—high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity—a new one has to be added, clonal hematopoiesis. This condition ...

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Ultrasound device shows promise for treating chronic pain

Pain is a necessary biological signal, but a variety of conditions can cause those signals to go awry. For people with chronic pain, the root is often faulty signals emerging deep within the brain, giving false alarms about ...

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Review highlights advances in kidney cancer research and care

New insights into the biology of kidney cancer, including those informed by scientific discoveries that earned a Nobel Prize, have led to advances in treatment and increased survival rates, according to a review by UNC Lineberger ...

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Key discovery advances fight to reduce breast cancer recurrence

In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in estrogen receptor-positive ...

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Study of pythons could lead to new therapies for heart disease

In the first 24 hours after a python devours its massive prey, its heart grows 25%, its cardiac tissue softens dramatically, and the organ squeezes harder and harder to more than double its pulse. Meanwhile, a vast collection ...

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Targeting a human protein to squash SARS-CoV-2, other viruses

More than two years into the COVID-19 pandemic, people are realizing that the "new normal" will probably involve learning to co-exist with SARS-CoV-2. Some treatments are available, but with new variants emerging, researchers ...

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What would it take to set up an African drug discovery ecosystem?

Africa has great potential for drug discovery. The continent has natural resources, indigenous knowledge and human capacity. And it has the need: it bears more than 20% of the global disease burden. There are many internationally ...

Medical research

A reference tissue atlas for the human kidney

A team of researchers including Jens Hansen, Rachel Sealfon, Rajastree Menon, and colleagues of the Kidney Precision Medicine Project, built on an existing specific human kidney tissue atlas relevant to health care at single-cell ...

Medical research

Researchers make headway into the function of the heart

An interdisciplinary team of researchers from Florida State University, University of Washington and The Ohio State University have discovered previously unknown chemical changes in a protein that contribute to a heart's ...

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Investigating mRNA-based antibiotics

In the fight against the COVID-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 ...

Medical research

Getting to the heart of heart muscle function

Every heart muscle cell, or cardiomyocyte, is studded with tiny, intricate structures called dyads. The dyads are like orchestra conductors: They coordinate incoming electrical signals with release of calcium in the muscle, ...

Medical research

Common prebiotic fiber mitigates harm of high-salt diet in rats

New research in rats finds a diet high in the prebiotic fiber inulin offered a protective effect against the damage of a high-salt diet. The research will be presented this week at the American Physiological Society (APS) ...

Medical research

Intermittent fasting protects kidneys of obese mice

New research in a mouse model of diet-induced obesity finds that time-restricted feeding improves markers of kidney and vascular health. The research will be presented this week at the American Physiological Society (APS) ...

Medical research

Scientists decipher the danger of gummy phlegm in severe COVID-19

Stanford University scientists have implicated a logjam of three long, stringy substances behind deadly thick sputum in COVID-19 patients who need a machine to help them breathe. One of these substances may prove especially ...