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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

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Study highlights association between urinary and vaginal pathogenic E. coli in recurrent cystitis

The human body hosts a diverse array of microorganisms that maintain a delicate balance crucial for overall health. This microbial harmony can be disrupted by factors such as infections, aging, and hormonal changes, leading ...

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Protein droplets likely don't cause Parkinson's, study suggests

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...

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Radiation therapy may be potential heart failure treatment

Cardiologists and radiation oncologists at Washington University School of Medicine in St. Louis pioneered the use of radiation therapy—a strategy typically used against cancer—to treat patients with a life-threatening ...

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Repairing nerve cells after injury and in chronic disease

Each year in the United States there are more than 3 million cases of peripheral neuropathy, wherein nerves outside of the brain and spinal cord are damaged and cause pain and loss of feeling in the affected areas. Peripheral ...

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Macaque trials offer hope in pneumonia vaccine development

The global impact of the coronavirus pandemic has ignited a renewed focus on emerging and re-emerging infectious diseases. Researchers at Osaka Metropolitan University are making great strides in combating pneumococcal pneumonia, ...

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Mixing heat with hair styling products may be bad for your health

Hair products often contain ingredients that easily evaporate, so users may inhale some of these chemicals, potentially posing health repercussions. Now, researchers have studied emissions of these volatile organic compounds ...

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Researchers identify way to block alphavirus infection

Researchers at Washington University School of Medicine in St. Louis have found an innovative way to block infection by a variety of alphaviruses, a group of mosquito-borne viruses that can cause joint and brain infections ...

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New clues into the head-scratching mystery of itch

Scientists at Harvard Medical School have shown for the first time that a common skin bacterium—Staphylococcus aureus—can cause itch by acting directly on nerve cells.

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Scientists discover key step to kidney fibrosis

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following ...

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A computer model of the ear may help to improve cochlear implants

Professor Pavel Jungwirth and his colleagues from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and the cochlear implant company MED-EL, based in Austria have come up with ...