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Medical research news

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

Medical research

Are AI-chatbots suitable for hospitals? Diagnostic capabilities of large language models tested

Large language models may pass medical exams with flying colors but using them for diagnoses would currently be grossly negligent. Medical chatbots make hasty diagnoses, do not adhere to guidelines, and would put patients' ...

Medical research

Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

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Highlighting dual-therapy-based Helicobacter pylori eradication

Helicobacter pylori (H. pylori) is an infectious bacterium that resides in the gastric mucosa and causes persistent gastric damage. H. pylori can cause chronic gastritis, peptic ulcers, and iron deficiency anemia. If left ...

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A new immune pathway sheds light on amyotrophic lateral sclerosis

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures. But researchers at Boston Children's Hospital and Harvard Medical School are looking for new pathways for slowing ...

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Calcium: A key player for a promising and safe brain treatment?

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)—specialized molecules that can modulate RNA and alter protein production—directly injected into the cerebrospinal fluid, in ...

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New method for detecting nanoplastics in blood

A new study has used flow cytometry to detect and measure nanoplastics in peripheral human blood. People with various medical conditions were included in the study so as to investigate potential differences for nanoplastic ...

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Exploring how the brain senses infection

A new study led by researchers at Harvard Medical School illuminates how the brain becomes aware that there is an infection in the body.

Medical research

Exploring how fungal spores hijack lung cells

The pathogenic fungus Aspergillus fumigatus escapes elimination from surface cells of the human lung by binding to a human protein. In doing so, it is able to nest in so called phagosomes, confined areas in the lung cells, ...

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Seeking leukemia's Achilles heel

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells. The authors published their results in Molecular & Cellular Proteomics.

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New approach to improving clinical trial enrollment and diversity

Before new therapies can reach patients, they must be tested in clinical trials in representative populations to show that they work and are safe. Failure to enroll enough participants in trials can delay the arrival of new ...

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Protein derived from bone may help combat osteosarcoma

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type of bone cancer.

Medical research

The case for female mice in neuroscience research

Mice have long been a central part of neuroscience research, providing a flexible model that scientists can control and study to learn more about the intricate inner workings of the brain. Historically, researchers have favored ...