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Data from largest Phase III trial of pre-symptomatic Alzheimer's disease now shared with scientists around the world

Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition. The ...

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Peptide cocktails show promise in combating antibiotic resistance

Antibiotics are essential tools in modern medicine, regularly used to treat bacterial infections and prevent infections during surgery. However, the widespread use of antibiotics has led to many bacteria developing resistance, ...

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Cure for male pattern baldness given boost by sugar discovery

The key to curing male pattern baldness—a condition that affects up to 50% of men worldwide—could lie in a sugar that naturally occurs in the human body, according to scientists at the University of Sheffield.

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Study finds tumor growth fueled by nucleotide salvage

Cancer cells salvage purine nucleotides to fuel tumor growth, including purines in foods we eat, an important discovery with implications for cancer therapies from research by Children's Medical Center Research Institute ...

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Premature birth linked to poorer school grades in adolescence

Premature birth, before 34 weeks of pregnancy, is linked to lower scores in math and language tests as a teenager compared with those born at 40 weeks, finds a large Danish population study published today in The BMJ.

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New research furthers case for exercise promoting youthfulness

A recent paper published in the Journal of Physiology deepened the case for the youthfulness-promoting effects of exercise on aging organisms, building on previous work done with lab mice nearing the end of their natural ...

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Probiotic markedly reduces S. Aureus colonization in phase 2 trial

A promising approach to control Staphylococcus aureus bacterial colonization in people—using a probiotic instead of antibiotics—was safe and highly effective in a Phase 2 clinical trial. The new study, reported in The ...

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New molecular blocker halts breast cancer metastasis, says study

An estimated ninety percent of deaths from breast cancer are due to complications resulting from metastasis, a process in which cancer cells break away from where they first formed, travel through the blood or lymph circulatory ...

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Protein movement reveals brain tumor's weak spot

Proteins do not have a single shape, but are more like dynamic robots. But—how do they actually move? And what does this tell us about their function? Laura Orellana describes the movement of proteins using computer simulations—and ...

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Improving treatment for hairy cell leukemia

Patients with relapsed or refractory hairy cell leukemia who were treated with vemurafenib experienced excellent response and relapse-free survival, according to a recent clinical trial published in Blood.

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Simple spray could keep COVID away

What if preventing respiratory illnesses such as COVID-19 and influenza could be as easy as a quick spritz of nasal spray every morning?

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Scientists find way to heal scars left behind by heart attacks

After a heart attack, the shock of the event leaves behind a trail of damaged heart muscle, which becomes a scar over time. However, the scar tissue doesn't have the elasticity and flexibility of healthy heart muscle, meaning ...

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Zebrafish model helps explain eye development

Scientists at the National Eye Institute (NEI) have developed a zebrafish model of NEDBEH—a rare genetic disorder that can cause coloboma, where parts of the eye are missing due to developmental defects. The model provides ...