Measuring just a few millimeters across, clusters of cultured cells that self-assemble into three-dimensional structures may look like just tiny blobs. But these tissues, called organoids, are enabling scientists to study ...
Sep 15, 2020
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SARS-CoV-2 can infect human neural progenitor cells and brain organoids, as shown by researchers from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences and their collaborators from The ...
Aug 25, 2020
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The scientists who developed the first 3-D multicellular brain organoid with a functional blood brain barrier now report that the model could be a promising platform to screen drugs that could work to control inflammation, ...
Jul 30, 2020
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The human brain is bathed in a supportive fluid called the cerebrospinal fluid (CSF) that provides nutrients and is required for proper brain function. The composition of human CSF and how it is made are poorly understood ...
Jun 12, 2020
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A City of Hope scientist is one step closer to discovering what weakens a pathogen that appears to cause babies to be born with abnormally small heads.
Mar 30, 2020
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When brains begin developing, there are a lot of moving parts—and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism. But scientists don't know much about the ways that ...
Mar 11, 2020
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Brain organoids—three-dimensional balls of brain-like tissue grown in the lab, often from human stem cells—have been touted for their potential to let scientists study the formation of the brain's complex circuitry in ...
Jan 29, 2020
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168
Hundreds of miniature brains were grown in the laboratories of the University of Trento to study the genetic mechanisms responsible for medulloblastoma, the most common brain cancer affecting children. The results of a collaborative ...
Jan 29, 2020
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Glioblastomas are the most aggressive form of brain cancer—they grow and spread rapidly through the brain and are virtually impossible to eradicate, typically leading to death within one or two years of diagnosis. Scientists ...
Jan 29, 2020
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A team of researchers at Stanford University has, for the first time, created three-dimensional organoid models of the human forebrain. In their paper published in the journal Science, the group describes growing the organoids ...
