Genetics
Breast cancer and heart disease may have common roots
Women who are at risk for breast cancer may also be at greater risk for heart disease, new research has found.
Dec 20, 2011
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Page 38 - News tagged with dna repair
Oncology & Cancer
Soybean compounds enhances effects of cancer radiotherapy
A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.
Dec 19, 2011
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Oncology & Cancer
'PARP' drug sabotages DNA repair in pre-leukemic cells
Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits ...
Dec 12, 2011
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Oncology & Cancer
Study identifies mechanisms cells use to remove bits of RNA from DNA strands
When RNA component units called ribonucleotides become embedded in genomic DNA, which contains the complete genetic data for an organism, they can cause problems for cells. It is known that ribonucleotides in DNA can potentially ...
Dec 4, 2011
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Medical research
Molecular corkscrew
Scientists from the universities of Zurich and Duisburg-Essen have discovered a specific function of the protein p97/VCP. They demonstrate that the protein repairs DNA breaks like a corkscrew, a repair mechanism that could ...
Nov 8, 2011
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Oncology & Cancer
First evidence of new 'druggable' DNA repair target to destroy cancer cells
(Medical Xpress) -- Blocking a key DNA damage repair enzyme, called APE1, could provide a new way to kill cancer cells containing faulty BRCA genes, according to research presented at the National Cancer Research Institute ...
Nov 7, 2011
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Oncology & Cancer
Findings suggest how cancer cells can become resistant to DNA damage-inducing treatments
An international team of scientists led by UC Davis researchers has discovered that DNA repair in cancer cells is not a one-way street as previously believed. Their findings show instead that recombination, an important DNA ...
Oct 23, 2011
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Oncology & Cancer
Ovarian cancer patients survive longer with BRCA2 mutated in tumors
Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute ...
Oct 11, 2011
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Oncology & Cancer
Bacteria shed light on new drug targets for inherited cancers
Cancer Research UK scientists have succeeded in purifying a protein found in bacteria that could reveal new drug targets for inherited breast and ovarian cancers - and other cancers linked to DNA repair faults. The study ...
Sep 6, 2011
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Oncology & Cancer
Olaparib shows promise in treating ovarian cancer, even without BRCA mutations
The PARP inhibitor, olaparib, that has shown promise in women with an inherited mutation in their BRCA1 or BRCA2 gene (accounting for about 5-10% of breast and ovarian cancer cases), has, for the first time, been shown to ...
Aug 21, 2011
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