A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.
Jan 21, 2020
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Since 1993, when the gene that causes Huntington's disease (HD) was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration. In a new ...
Apr 3, 2019
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An MDC research team reports in the journal Molecular Cell that short protein fibers precede the formation of larger deposits that accumulate in the brains of those affected by the incurable Huntington's disease, sometimes ...
Sep 6, 2018
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A new study published in the Proceedings of the National Academy of Sciences (PNAS) suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling ...
Sep 5, 2018
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Neuroscientist Dr. David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step toward understanding the mechanisms that cause the neurodegenerative ...
Jul 27, 2018
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McMaster University researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition.
Jul 9, 2018
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Neurological diseases are typically associated with a multitude of molecular changes. But out of these thousands of changes in gene expression, which ones are actually driving the disease? To answer this question, a team ...
Jun 20, 2018
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A new variant of the gene-editing CRISPR/Cas9 system is safer and more specific than versions previously used in early research towards a treatment for Huntington's disease, shows research published today in Frontiers in ...
Feb 26, 2018
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Disrupting a problematic gene in brain cells can reverse Huntington's disease pathology and motor symptoms in a mouse model of the inherited neurological disorder, scientists report.
Jun 19, 2017
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Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center—the nucleus—appear to be a ...
May 4, 2017
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