Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are degenerative motor neuron diseases in which the key mutated genes are involved in RNA metabolism. This similarity suggests that a common dysregulation ...
Apr 26, 2013
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Melatonin injections delayed symptom onset and reduced mortality in a mouse model of the neurodegenerative condition amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, according to a new study by researchers at ...
Apr 25, 2013
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Neurodegenerative diseases are characterized by the aggregation of misfolded proteins, which accumulate to form insoluble clumps within or around nerve cells. In the adult motor neuron disease amyotrophic lateral sclerosis ...
Apr 22, 2013
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Dalhousie neurosurgeon and scientist Dr. Rob Brownstone and postdoctoral fellow Dr. Tuan Bui have identified the spinal cord circuit that controls the hand's ability to grasp. This breakthrough finding opens the door to the ...
Apr 10, 2013
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Spinal muscular atrophy is a debilitating neuromuscular disease that in its most severe form is the leading genetic cause of infant death. By experimenting with an ALS drug in two very different animal models, researchers ...
Apr 9, 2013
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A team of researchers, led by Marc Freeman, PhD, an early career scientist with the Howard Hughes Medical Institute and associate professor of neurobiology at the University of Massachusetts Medical School have discovered ...
Apr 8, 2013
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Biologists from the Ruhr-Universität Bochum have explored how to protect neurons that control movements from dying off. In the journal Molecular and Cellular Neuroscience they report that the molecule 7,8-Dihydroxyflavone, ...
Apr 2, 2013
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(Medical Xpress)—Results from a clinical trial into amyotrophic lateral sclerosis (ALS), led by King's College London's Institute of Psychiatry show that lithium carbonate is ineffective at treating the disease.
Mar 19, 2013
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New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget's Disease of the Bone ...
Mar 14, 2013
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A University of Connecticut researcher is advancing the understanding of the devastating inherited condition known as spinal muscular atrophy.
Jan 29, 2013
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