Borrelia burgdorferi, the bacterium that causes Lyme disease, hitchhikes in ticks for dissemination to mammalian hosts—including humans. An article in the 19 December issue of PLOS Pathogens identifies HrpA, an RNA helicase, ...
Dec 19, 2013
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A mosquito-borne virus that kills about half of the people it infects uses a never-before-documented mechanism to "hijack" one of the cellular regulatory systems of its hosts to suppress immunity, according to University ...
Dec 18, 2013
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Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have generated the first known disease-specific induced pluripotent stem cell (iPSC) lines from a patient with familial transthyretin ...
Oct 31, 2013
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Mood and emotion are extremely complex aspects of behavior that are known to involve the neurotransmitters serotonin and norepinephrine. Both neurotransmitters are broken down by an enzyme called monoamine oxidase A (MAO-A), ...
Oct 11, 2013
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Hypertrophic cardiomyopathy (HCM), a disease in which cardiac muscle thickens, weakening the heart, can be prevented from developing for several months in mice by reducing production of a mutant protein, according to a new ...
Oct 3, 2013
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The cerebellum is a region of the brain critical for balance, learning of motor skills and coordination of movements. In the outer layer of the cerebellum, individual 'Purkinje' cells integrate inputs from the brain stem ...
Sep 20, 2013
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Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers. This strategy works by sabotaging the ability of ...
Sep 18, 2013
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Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches ...
Sep 12, 2013
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(Medical Xpress)—A genetic mutation that can lead to haemorrhagic stroke has been identified by scientists – along with a drug to potentially treat it.
Sep 4, 2013
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During formation of the vascular system, successively smaller blood vessels sprout from existing ones to form networks of capillaries in patterns uniquely adapted to the function of the organ they enter. This process, called ...
Aug 30, 2013
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