Genetics

Epigenetics and neural cell death

Ludwig-Maximilians-Universitaet researchers have demonstrated how deregulation of an epigenetic mechanism that is active only in the early phases of neurogenesis triggers the subsequent death of neural cells.

Neuroscience

The balancing act to regulate the brain machinery

Molecular imbalance lies at the root of many psychiatric disorders. Current EU-funded research has discovered a major RNA molecular player in neurogenesis and has characterised its action and targets in the zebrafish embryo.

Neuroscience

Lithium restores cognitive function in Down syndrome mice

Down syndrome is a neurodevelopmental disorder that is the leading cause of genetically defined intellectual disability. In the brain, Down syndrome results in alterations in the connections between neurons and a reduction ...

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