(Medical Xpress) -- A study published in Genes and Development from scientists at the Friedrich Miescher Institute for Biomedical Research pinpoints the importance of maternal epigenetic influences during early embryogenesis ...
May 7, 2012
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In one of the first genome-wide studies to hunt for both genes and their regulatory "tags" in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid ...
Jan 20, 2013
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Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The ...
Jun 9, 2020
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CHARGE syndrome is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the ...
Jul 5, 2013
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Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. Now, FMI researchers have identified a DNA region containing multiple regulatory elements that interact ...
Jun 6, 2023
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Multiple sclerosis (MS) is an autoimmune disease in which the immune system turns on its own cells and attacks them for reasons that are not yet known. Scientists from the Institut Pasteur have shown that ancient viruses ...
May 13, 2019
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Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 million base pairs away from ...
May 8, 2023
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Researchers at the University of Washington have determined that the majority of genetic changes associated with more than 400 common diseases and clinical traits affect the genome's regulatory circuitry. These are the regions ...
Sep 5, 2012
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Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body. Moreover, fat processing ...
Jan 12, 2022
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(Medical Xpress)—More than a million people die each year of malaria caused by different strains of the Plasmodium parasite transmitted by the Anopheles mosquito. The medical world has yet to find an effective vaccine against ...
Dec 3, 2012
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