Medications

Countering the negative effects of a common antidepressant

Selective serotonin reuptake inhibitors, or SSRI's, are popular drugs that treat depression by increasing the amount of a neurotransmitter called serotonin in the brain. But when a common SSRI known as sertraline is taken ...

Neuroscience

Why some people are more prone to anxiety

Anxiety-prone people can blame serotonin cleanup proteins gone awry in their amygdala, according to research in marmosets recently published in JNeurosci. Targeting the amygdala with anti-anxiety medication could provide ...

Serotonin

"Serotonin" redirects here. For the professional wrestling stable, see Serotonin.

Serotonin (pronounced /ˌsɛrəˈtoʊnən/) is a monoamine neurotransmitter. It is found extensively in the gastrointestinal tract of animals, and about 80 to 90 percent of the human body's total serotonin is located in the enterochromaffin cells in the gut, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic neurons in the central nervous system (CNS) where it has various functions, including control of appetite, mood and anger.

Serotonin is found not only in animals, but also in fungi and plants, including fruits and vegetables.

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