Psychology & Psychiatry

How fear transforms into anxiety

A deadly coronavirus pandemic, economic instability and civil unrest menace the mental well-being of millions. Understanding how, in vulnerable people, fear from such frightening events evolves into lifelong anxiety, is critical ...

Medical research

Gut Piezo1 regulates gut and bone homeostasis via RNA sensing

Gut enterochromaffin cells regulate gut and bone homeostasis via serotonin production. A recent report suggested that gut microbes regulate serotonin levels, but the underlying molecular mechanisms are unexplored. Here, Piezo1 ...

Serotonin

"Serotonin" redirects here. For the professional wrestling stable, see Serotonin.

Serotonin (pronounced /ˌsɛrəˈtoʊnən/) is a monoamine neurotransmitter. It is found extensively in the gastrointestinal tract of animals, and about 80 to 90 percent of the human body's total serotonin is located in the enterochromaffin cells in the gut, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic neurons in the central nervous system (CNS) where it has various functions, including control of appetite, mood and anger.

Serotonin is found not only in animals, but also in fungi and plants, including fruits and vegetables.

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