Smoking status is an important patient-related prognostic factor for outcome in patients with acute myeloid leukemia (AML) treated with intensive chemotherapy, according to a study published online April 21 in the British ...
Apr 30, 2020
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Next-generation cancer strategies rely on next-generation gene sequencing (NGS), which paves the way for new techniques and tools to detect mutations and determine patient therapy. A team of Chinese researchers proposed a ...
Feb 1, 2023
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A new editorial perspective titled "Genetic modifiers of p53: opportunities for breast cancer therapies" has been published in Oncotarget.
Oct 25, 2023
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Researchers in China have reported the first large-scale study characterizing the proteomics and phosphoproteomics of small cell lung cancer (SCLC) clinical cohorts, providing a comprehensive picture of the proteogenomics ...
Feb 27, 2024
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(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study published in ...
Mar 8, 2012
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A new research paper has been published in Oncotarget, titled "NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer."
May 25, 2022
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Having a child with a developmental disorder can cause parents to worry about the outcome of further pregnancies. In cases where the genetic mutation causing the disorder is not present in either parent, it is assumed to ...
Jun 17, 2019
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Whole genome sequencing using long fragment read (LFR), a technology that can analyze the entire genomic content of small numbers of cells, detected potentially targetable mutations using only five circulating tumor cells ...
Aug 15, 2017
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Children with bilateral Wilms tumor have a tumor in each of their kidneys—a condition that strongly suggests an underlying genetic or epigenetic predisposition driving the disease. Scientists at St. Jude Children's Research ...
Dec 18, 2023
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A new computational method developed by researchers at the New York Genome Center (NYGC) allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity than currently available approaches.
Mar 22, 2018
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