People diagnosed with cancer are at a greater risk of mental health problems even five years after their diagnosis, according to a large-scale study of data from UK GP patient records.
Sep 17, 2024
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Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new ...
Sep 15, 2024
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Melanoma rates differ consistently between men and women in terms of the ages at which melanomas occur and the locations on the body where they occur. Over time, melanoma rates have increased in both men and women, but the ...
Sep 12, 2024
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About 8 to 10 million Americans over age 40 have an overabundance of cloned white blood cells, or lymphocytes, that hamper their immune systems. Although many who have this condition—called monoclonal B-cell lymphocytosis ...
Sep 6, 2024
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Age-related changes in the fibroblasts, cells that create the skin's structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the Johns Hopkins Kimmel ...
Sep 6, 2024
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Researchers from QIMR Berghofer have found that declining melanoma rates among young Australians have been influenced by the country's increasingly diverse population and more varied skin tones.
Sep 3, 2024
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A new paper published in the journal Nature Communications explores programmed cell death (PD-1) in melanoma cells and the immune system's response.
Aug 28, 2024
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There are three major kinds of skin cancer—squamous cell carcinoma, basal cell carcinoma and melanoma. Melanoma is the most dangerous. The first sign of melanoma is a change in an existing mole or a new, unusual-looking ...
Aug 28, 2024
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A new research paper titled "Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival" has been published in Oncotarget.
Aug 8, 2024
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A new editorial paper titled "How to deal with runaway metastatic disease?" has been published in Oncotarget.
Aug 7, 2024
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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
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