Melanoma
New study reveals how tumor suppressor p53 shut down in metastatic melanoma
Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way ...
Cancer
Apr 25, 2013 |
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Researchers observe an increased risk of cancer in people with history of non-melanoma skin cancer
A prospective study by researchers at Brigham and Women's Hospital (BWH) observed an association between risk of second primary cancer and history of non-melanoma skin cancer in white men and women.
Cancer
Apr 23, 2013 |
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Virus kills melanoma in animal model, spares normal cells
Researchers from Yale University School of Medicine have demonstrated that vesicular stomatitis virus (VSV) is highly competent at finding, infecting, and killing human melanoma cells, both in vitro and in animal models, ...
Medical research
Apr 23, 2013 |
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NZ outdoor workers poorly protected from the sun, researchers find
New Zealand outdoor workers are generally poorly protected from solar UV radiation, with only around one-third wearing sunscreen or a suitably protective hat, according to a University of Otago study published ...
Health
Apr 23, 2013 |
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Three unique genes found to influence body size and obesity in people of African ancestry
Researchers from Dartmouth's Institute for Quantitative Biomedical Sciences (iQBS) and the Center for Genomic Medicine have helped to discover three unique genetic variations that influence body size and obesity in men and ...
Genetics
Apr 22, 2013 |
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Blocking 'scaffold' protein inhibits cancer growth, study finds
(Medical Xpress)—Researchers at the Stanford University School of Medicine have devised an entirely novel way to block biological signaling pathways that, when overactive, lead to many types of cancers. They've done so ...
Cancer
Apr 22, 2013 |
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Photoacoustics spares healthy lymph nodes in patients with metastasized cancer
If a tumour has spread through the lymph nodes, the decision is often taken to exercise caution and remove extra tissue, to prevent it from spreading further. This often involves the removal of healthy lymph ...
Cancer
Apr 18, 2013 |
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Researchers abuzz over caffeine as cancer-cell killer
(Medical Xpress)—Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells—results that could one day ...
Cancer
Apr 18, 2013 |
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Completion of the zebrafish reference genome yields strong comparisons with the human genome
Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart. ...
Genetics
Apr 17, 2013 |
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CT and serum LDH shows promise as survival predictor for some metastatic melanoma patients
Combining CT imaging findings with baseline serum lactate dehydrogenase levels is showing promise as a way to predict survival in patients with metastatic melanoma being treated with anti-angiogenic therapy.
Cancer
Apr 17, 2013 |
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Spread of breast cancer linked to kisspeptins which normally inhibit metastasis
KISS 1 is a metastasis-suppressor gene which helps to prevent the spread of cancers, including melanoma, pancreatic and ovarian cancers to name a few. But new research from Western University's Schulich School of Medicine ...
Cancer
Apr 16, 2013 |
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Transcription factors regulating blood oxygen linked to melanoma metastases
Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.
Cancer
Apr 16, 2013 |
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Lower education linked to premature death from malignant skin melanoma
There are socioeconomic differences in Sweden in survival amongst people with malignant skin melanoma, according to a new study published in the European Journal of Cancer. Melanoma patients with a lower educational backgr ...
Cancer
Apr 16, 2013 |
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Pediatric melanomas are increasing two percent a year
(HealthDay)—The incidence of pediatric melanoma has increased by about 2 percent per year, and this incidence trend is influenced by gender, age, and stage at diagnosis, primary site, and ultraviolet (UV)-B ...
Pediatrics
Apr 16, 2013 |
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In-transit melanoma advance is difficult to predict
(HealthDay)—Progressive disease cannot be reliably predicted by patient, clinical, or procedural factors in patients receiving regional therapy for advanced melanoma of the extremities, according to a study ...
Surgery
Apr 15, 2013 |
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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.
Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.
The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
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