Melanoma

New study reveals how tumor suppressor p53 shut down in metastatic melanoma

Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way ...

Cancer created Apr 25, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers observe an increased risk of cancer in people with history of non-melanoma skin cancer

A prospective study by researchers at Brigham and Women's Hospital (BWH) observed an association between risk of second primary cancer and history of non-melanoma skin cancer in white men and women.

Cancer created Apr 23, 2013 | popularity not rated yet | comments 0

Virus kills melanoma in animal model, spares normal cells

Researchers from Yale University School of Medicine have demonstrated that vesicular stomatitis virus (VSV) is highly competent at finding, infecting, and killing human melanoma cells, both in vitro and in animal models, ...

Medical research created Apr 23, 2013 | popularity 5 / 5 (2) | comments 0

NZ outdoor workers poorly protected from the sun, researchers find

New Zealand outdoor workers are generally poorly protected from solar UV radiation, with only around one-third wearing sunscreen or a suitably protective hat, according to a University of Otago study published ...

Health created Apr 23, 2013 | popularity not rated yet | comments 0

Three unique genes found to influence body size and obesity in people of African ancestry

Researchers from Dartmouth's Institute for Quantitative Biomedical Sciences (iQBS) and the Center for Genomic Medicine have helped to discover three unique genetic variations that influence body size and obesity in men and ...

Genetics created Apr 22, 2013 | popularity not rated yet | comments 1

Blocking 'scaffold' protein inhibits cancer growth, study finds

(Medical Xpress)—Researchers at the Stanford University School of Medicine have devised an entirely novel way to block biological signaling pathways that, when overactive, lead to many types of cancers. They've done so ...

Cancer created Apr 22, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Photoacoustics spares healthy lymph nodes in patients with metastasized cancer

If a tumour has spread through the lymph nodes, the decision is often taken to exercise caution and remove extra tissue, to prevent it from spreading further. This often involves the removal of healthy lymph ...

Cancer created Apr 18, 2013 | popularity not rated yet | comments 0

Researchers abuzz over caffeine as cancer-cell killer

(Medical Xpress)—Researchers from the University of Alberta are abuzz after using fruit flies to find new ways of taking advantage of caffeine's lethal effects on cancer cells—results that could one day ...

Cancer created Apr 18, 2013 | popularity 4.6 / 5 (11) | comments 0 | with audio podcast

Completion of the zebrafish reference genome yields strong comparisons with the human genome

Researchers demonstrate today that 70 per cent of protein-coding human genes are related to genes found in the zebrafish and that 84 per cent of genes known to be associated with human disease have a zebrafish counterpart. ...

Genetics created Apr 17, 2013 | popularity not rated yet | comments 0 | with audio podcast

CT and serum LDH shows promise as survival predictor for some metastatic melanoma patients

Combining CT imaging findings with baseline serum lactate dehydrogenase levels is showing promise as a way to predict survival in patients with metastatic melanoma being treated with anti-angiogenic therapy.

Cancer created Apr 17, 2013 | popularity not rated yet | comments 0

Spread of breast cancer linked to kisspeptins which normally inhibit metastasis

KISS 1 is a metastasis-suppressor gene which helps to prevent the spread of cancers, including melanoma, pancreatic and ovarian cancers to name a few. But new research from Western University's Schulich School of Medicine ...

Cancer created Apr 16, 2013 | popularity not rated yet | comments 0

Transcription factors regulating blood oxygen linked to melanoma metastases

Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.

Cancer created Apr 16, 2013 | popularity not rated yet | comments 0 | with audio podcast

Lower education linked to premature death from malignant skin melanoma

There are socioeconomic differences in Sweden in survival amongst people with malignant skin melanoma, according to a new study published in the European Journal of Cancer. Melanoma patients with a lower educational backgr ...

Cancer created Apr 16, 2013 | popularity not rated yet | comments 0

Pediatric melanomas are increasing two percent a year

(HealthDay)—The incidence of pediatric melanoma has increased by about 2 percent per year, and this incidence trend is influenced by gender, age, and stage at diagnosis, primary site, and ultraviolet (UV)-B ...

Pediatrics created Apr 16, 2013 | popularity not rated yet | comments 0

In-transit melanoma advance is difficult to predict

(HealthDay)—Progressive disease cannot be reliably predicted by patient, clinical, or procedural factors in patients receiving regional therapy for advanced melanoma of the extremities, according to a study ...

Surgery created Apr 15, 2013 | popularity not rated yet | comments 0


Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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