Melanoma

Report finds continuing challenges in changing behaviors that increase cancer risk

An annual report from the American Cancer Society finds continuing challenges in changing behaviors and risk factors in order to reduce suffering and death from cancer. The report, Cancer Prevention & Early Detection Facts ...

Cancer created Apr 11, 2013 | popularity 5 / 5 (1) | comments 0

Mining information contained in clinical notes could yield early signs of harmful drug reactions

Mining the records of routine interactions between patients and their care providers can detect drug side effects a couple of years before an official alert from the U.S. Food and Drug Administration, a Stanford University ...

Medications created Apr 10, 2013 | popularity not rated yet | comments 0 | with audio podcast

Naturally occurring substance proves effective against deadly skin cancer in laboratory tests

For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

New target plus new drug equals death of melanoma cells

Collaborative research presented by the University of Colorado Cancer Center, the University of North Carolina at Chapel Hill, Harvard Medical School and the University of Pittsburgh, at the American Association for Cancer ...

Cancer created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0

Some melanoma survivors still use tanning beds, skip sunscreen

Although most survivors of melanoma take precautions to protect their skin from the sun and further occurrences of cancer, data presented at the AACR Annual Meeting 2013, held in Washington, D.C., April 6-10, revealed that ...

Cancer created Apr 09, 2013 | popularity not rated yet | comments 0

Intermittent treatment with vemurafenib may prevent lethal drug resistance in melanoma

Vemurafenib-resistant tumors in patients with melanoma showed reduced growth after cessation of treatment, and in animal models, drug resistance was prevented by intermittent treatment, according to data presented at the ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Preclinical study indicates potential for novel inhibitor to overcome drug resistance induced by RAF, MEK inhibitors

A new class of investigational medicines may help to treat patients with cancers driven by mutations in genes such as BRAF or KRAS/NRAS, including those patients who have become resistant to therapies that target BRAF directly, ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

BRAF mutation less common among patients with melanoma in Ireland

The BRAF mutation believed to drive disease in about half of patients with melanoma was found to occur at a significantly lower frequency in patients with melanoma in Ireland, according to data presented at the AACR Annual ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Study reveals how melanoma evades chemotherapy

Nitric oxide (NO), a gas with many biological functions in healthy cells, can also help some cancer cells survive chemotherapy. A new study from MIT reveals one way in which this resistance may arise, and ...

Cancer created Apr 08, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Individualized genomic testing allows for tailored cancer treatment, new drug research

Just like a massive iceberg jutting out of the ocean, many of cancer's genetic underpinnings remain hidden under the surface, impossible to predict or map from above. The foreboding shadows and shapes that appear on CT scans ...

Cancer created Apr 05, 2013 | popularity not rated yet | comments 0

Shutting down DNA construction: How senescence halts growth of potential cancers

Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks ...

Cancer created Apr 04, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Melanoma rates rising in US children

(HealthDay)—Melanoma, the most deadly form of skin cancer, doesn't usually occur in kids, but a new study shows that it's happening more often.

Cancer created Apr 03, 2013 | popularity 5 / 5 (2) | comments 0

Third-generation device significantly improves capture of circulating tumor cells

A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does ...

Cancer created Apr 03, 2013 | popularity not rated yet | comments 0 | with audio podcast

Researchers help test cancer drug in clinical trial leading to FDA approval

The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute (TGen).

Cancer created Mar 27, 2013 | popularity not rated yet | comments 0

Details of gene pathways suggest fine-tuning drugs for child brain tumors

Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments. A new study offers glimpses into how scientists ...

Cancer created Mar 26, 2013 | popularity not rated yet | comments 0 | with audio podcast


Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

This text uses material from Wikipedia and is available under the GNU Free Documentation License.

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