A stimulating environment keeps the "hippocampus"—which is the brain's memory control center—young, so to speak. Causes of this are molecular mechanisms that affect gene regulation. These current findings from studies ...
Jun 29, 2021
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The same mechanism that stabilises the DNA in the cell nucleus is also important for the structure and function of vertebrate muscle cells. This has been established by RUB-researchers led by Prof. Dr. Wolfgang Linke (Institute ...
Jan 23, 2012
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Injuries that result in chronic pain, such as limb injuries, and those unrelated to the brain are associated with epigenetic changes in the brain which persist months after the injury, according to researchers at McGill University. ...
Feb 15, 2013
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The research group led by immunologists Vigo Heissmeyer and Taku Ito-Kureha of LMU and Helmholtz Munich has revealed the essential function of m6A modifications in T cells.
Jul 27, 2022
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A team of scientists in Japan has found that a DNA modification called 5hmC – thought to be involved in turning genes on and off – localizes at sites of DNA damage and repair. They also found that a family of recently ...
Feb 11, 2016
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Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.
Sep 6, 2023
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Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer, ...
Jan 10, 2013
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To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. Now, new research shows how ...
Nov 28, 2016
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Purdue University and Indiana University School of Medicine scientists were able to force an epigenetic reaction that turns on and off a gene known to determine the fate of the neural stem cells, a finding that could lead ...
Feb 14, 2017
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Depression is a common mental health problem that affects people across demographics. Scientists have long known that there may be a genetic component that confers predisposition to depression, but the specific underlying ...
Sep 7, 2023
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