Epigenetics study finds 'jumping genes' support immune cells in tissue
Researchers at the Leibniz Institute for Immunotherapy (LIT) describe a new type of regulation of immune cells by so-called "jumping genes."
Jul 23, 2024
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Genetic Phenomena: News and Research on Interspersed Repetitive Sequences
MeSH tree: G05.360.340.024.425
Transposons could be new targets for aging research and treatment
A new USC Leonard Davis School-led study highlights how transposons—commonly called "jumping genes" because of their ability to move to different parts of the genome—are associated with age-related disease and decline, ...
Jun 17, 2024
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Researchers explore the role of of transposable elements in myocarditis
Regarded historically as genomic parasites, transposable elements (TEs) have now been recognized as significant contributors to cellular identity and function, especially in immune regulation.
May 15, 2024
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Exposing hiding lymphoma cells to the immune system
A study led by the group of Didier Trono at EPFL has revealed a crucial survival tactic employed by cancer cells. The scientists have identified a group of proteins, known as "KRAB zinc finger proteins" (KZFPs), that help ...
Feb 12, 2024
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Protein TDP-43 keeps genetic zombies at bay: New insights into neurodegenerative disease mechanisms
A new Cell Reports paper from Bing Yao's lab in Emory's Department of Human Genetics provides insights into mechanisms underlying several neurodegenerative diseases, such as ALS (amyotrophic lateral sclerosis) and Alzheimer's.
Jan 24, 2024
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New tool reveals the impact of 'jumping genes' on diseases
RIKEN geneticists have developed a tool that can quickly and accurately analyze variants in mobile genetic elements, commonly known as "jumping genes." This promises to shed light on the role such variants play in disease.
Oct 31, 2023
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'Jumping genes' found to alter human colon genomes, offering insights into aging and tumorigenesis
The Korea Advanced Institute of Science and Technology (KAIST) and their collaborators have conducted a groundbreaking study targeting "jumping genes" in the entire genomes of the human large intestine.
May 25, 2023
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A cancer-wide analysis finds cancer-wide targets for tumor reduction
Researchers at the Washington University School of Medicine, St. Louis, have discovered a potential new target for cancer immunotherapy in transposable elements (TEs), short segments of DNA that can move around the genome.
'Jumping' genes yield new clues to origins of neurodegenerative disease
Massive, repetitive stretches of DNA in the human genome may harbor hints about the onset of a rare, inherited neurodegenerative disorder called ataxia-telangiectasia as well as other related diseases, a new Yale School of ...
Sep 6, 2022
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Hallmark cancer gene regulates RNA 'dark matter'
A key genetic mutation that occurs early on in cancer alters RNA "dark matter" and causes the release of previously unknown RNA biomarkers for cancer early detection, a new study by UC Santa Cruz researchers published in ...
Jul 19, 2022
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