Adiposity, hyperglycemia tied to cognitive performance

February 1, 2013
Adiposity, hyperglycemia tied to cognitive performance
Among healthy middle-aged adults, adiposity and hyperglycemia correlate with poor cognitive performance, according to a study published online Dec. 28 in Diabetes Care.

(HealthDay)—Among healthy middle-aged adults, adiposity and hyperglycemia correlate with poor cognitive performance, according to a study published online Dec. 28 in Diabetes Care.

Caroline M. Sanz, M.D., from the University of Toulouse in France, and colleagues examined the correlation between markers of , markers of adiposity, (HbA1c), and cognitive performance in a sample of 1,172 adults aged 35 to 64 years without diabetes.

The researchers found that, in tests evaluating processing speed, elevated markers of adiposity correlated with poor cognitive performance. In each test, the probability of being in the lowest quartile was significantly increased for participants in the upper versus the lowest quartile of (adjusted odds ratio [OR], 2.18 for digit symbol substitution test [DSST]; OR, 2.09 for Stroop test). Poor cognitive performance in the DSST was also significantly more likely for those with high HbA1c (adjusted OR, 1.75). In men, but not women, was linked to poor cognitive performance.

"In a population of middle-aged adults without diabetes, we found that adiposity and a high level of HbA1c were both associated with poor cognitive performance in tests assessing processing speed," the authors write.

Explore further: Diabetes, poor glucose control associated with greater cognitive decline in older adults

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

White matter structural changes ID'd in children with T1DM

September 17, 2012

(HealthDay)—Children with type 1 diabetes have significant structural differences in the white matter of their brain compared to healthy children, which correlates with hemoglobin A1c (HbA1c) values, according to a study ...

Sleep apnea severity linked to glycated hemoglobin levels

June 18, 2012

(HealthDay) -- For adults without diabetes, obstructive sleep apnea (OSA) severity is independently associated with impaired glucose metabolism, as measured by glycated hemoglobin (HbA1c) levels, according to a study published ...

Meds adherence self-report valid in type 2 diabetes

December 20, 2012

(HealthDay)—Self-reported measures of medication adherence in adults with type 2 diabetes are valid, although some self-reports are moderated by depression, according to a study published online Nov. 30 in Diabetes Care.

Recommended for you

Post-biotics may help shield obese from diabetes

April 20, 2017

You've heard of pre-biotics and pro-biotics, but now you'll be hearing a lot more about post-biotics. Researchers at McMaster University have begun to identify how post-biotics, or the by-products of bacteria, lower blood ...

Diabetes continues its relentless rise

April 13, 2017

(HealthDay)—Two new studies on diabetes deliver good and bad news, but the overall message is that the blood sugar disease remains a formidable public health burden.

Researchers unravel how stevia controls blood sugar levels

April 11, 2017

What makes stevia taste so extremely sweet? And how does the sweetener keep our blood sugar level under control? Researchers at KU Leuven (University of Leuven, Belgium) have discovered that stevia stimulates a protein that ...

1 comment

Adjust slider to filter visible comments by rank

Display comments: newest first

not rated yet Feb 02, 2013
Doesn't it make sense that having a poor BMI is associated with a poor sell image which in turn is a marker of depression. If you are depressed your cognitive perfornance suffers

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.