This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:


peer-reviewed publication

trusted source


Exercise may reduce negative effects of unhealthy sleep duration on longevity

Credit: Unsplash/CC0 Public Domain

Sleeping too little or too long is linked with a shorter life, but scientists have found that physical activity counteracts some of these negative effects. The research in more than 90,000 adults is published today in the European Journal of Preventive Cardiology.

"The study showed that increased physical activity levels weakened the mortality risks associated with short or long sleep duration," said study author Dr. Jihui Zhang of The Affiliated Brain Hospital of Guangzhou Medical University, China.

Both sufficient and contribute to prolonged life expectancy. However, it has been unclear how physical activity may interact with sleep duration to promote health. The main limitation of previous studies was the use of self-reported physical activity and sleep, which is subjective and may be inaccurate. In contrast, an accelerometer device records movement, thereby providing objective and more reliable estimates of activity and sleep duration.

This was the first study to examine the joint effects of physical activity and sleep duration on mortality risk using accelerometry. The study included 92,221 adults aged 40 to 73 years in the UK Biobank cohort who wore an accelerometer wristband for one week between 2013 and 2015.

Sleep duration per night was classified as short (less than six hours), normal (six to eight hours) or long (more than eight hours). Total volume of physical activity was divided into tertiles (low, intermediate, high). Moderate to vigorous physical activity was classified as meeting World Health Organization (WHO) guidelines or not. Mortality data were collected from registries. The primary outcome was all-cause death. The secondary endpoints were death due to and death due to cancer.

The average age of participants was 62 years and 56% were women. During a median follow up of seven years, 3,080 participants died—1,074 from cardiovascular disease and 1,871 from cancer.

The researchers examined how physical activity influenced sleep's impact on mortality—first looking at the volume of activity and second at moderate to vigorous physical activity. The analyses were adjusted for factors that could influence the relationship including age, sex, ethnicity, deprivation, , season of sleep measurement, body mass index, diet, smoking, alcohol intake and shift work.

Regarding the volume of activity, in those with low amounts, short and long sleep were associated with 16% and 37% raised risks of all-cause death, respectively. In participants with intermediate amounts of exercise, only was detrimental, with a 41% raised likelihood of all-cause death. In those with a high amount of exercise, sleep duration was not linked with risk of death. For cardiovascular death, with a low volume of exercise had a 69% elevated risk, which disappeared when exercise increased to moderate or high volumes. For cancer death, long sleepers with low amounts of exercise had a 21% raised risk which disappeared with moderate or high volumes of exercise.

Similar results were found for moderate to vigorous physical activity. In participants not meeting the WHO recommendations, short and long sleep were associated with 31% and 20% raised risks of all-cause death, respectively. These risks disappeared in those meeting the WHO advice. For cardiovascular death, short sleepers who failed to meet the advice on intensity of exercise had a 52% elevated risk, which disappeared in those achieving the recommendations. For cancer death, long sleepers not meeting the advice had a 21% raised risk which disappeared in those following the WHO guidance.

Dr. Zhang said, "Our findings suggest that health promotion efforts targeting both physical activity and may be more effective in preventing or delaying premature death in middle-aged and than focusing on one behavior alone. In an ideal scenario, people would always get healthy amounts of both sleep and . However, our study indicates that getting sufficient exercise may partially offset the detrimental impact of missing a good night's sleep."

More information: Jihui Zhang et al, Joint Association of Physical Activity and Sleep Duration with Risk of All-cause and Cause-specific Mortality: A Population-Based Cohort Study Using Accelerometry, European Journal of Preventive Cardiology (2023). DOI: 10.1093/eurjpc/zwad060

Citation: Exercise may reduce negative effects of unhealthy sleep duration on longevity (2023, March 29) retrieved 22 September 2023 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Optimal sleep linked to lower risks for dementia and early death


Feedback to editors