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Vitamin D analog shuts down pancreatic cancer's shield in a clinical trial
A small clinical trial led by Dana-Farber Cancer Institute researchers has put a Salk Institute idea to the test in patients: that activating the vitamin D receptor can help reshape the protective environment surrounding ...
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Blocking two cancer pathways may curb medulloblastoma relapse, preclinical study suggests
For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are encouraging. But for a subset, remission is not the end of the story. Roughly 30% of patients will see ...
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Medical research news
Hidden brain circuit could explain how movement errors sharpen new skills
While humans are acquiring new skills that entail performing coordinated movements, such as walking, playing an instrument or skateboarding, their brains are known to continuously detect mistakes and correct movements over ...
Case of mistaken patterns: Slow brain development linked to ADHD for years might just be sex differences
Figuring out the causes of why children develop attention-deficit/hyperactivity disorder (ADHD) has been on scientists' radar for a few decades now. A common notion that has been around for nearly 20 years is that ADHD is ...
AI uncovers why squeezed tumors grow slower under physical pressure
Researchers have solved a long-standing mystery about why physical forces slow cancer growth—and the answer could reshape how the disease is treated. A multidisciplinary team from University of Galway, CÚRAM, the Taighde ...
3 hours ago
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The nocebo effect: How prior experience and verbal suggestion rewire the brain to make pain worse
Researchers have a better understanding of the nocebo effect and the neuroscience behind it all. Opposite of the better-known placebo effect, where positive expectations trigger genuine pain relief, the nocebo effect is the ...
3 hours ago
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Immune memory cells in ovarian cancer produce tumor-targeting antibodies, opening a vaccine path
While we tend to quickly forget having been ill or having received a vaccine, the immune system remembers remarkably well. It has memory B cells—"trained" immune cells that circulate throughout the body in search of harmful ...
4 hours ago
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New York families face maze to secure Medicaid-funded home care, secret shopper calls reveal
Obtaining home care for older adults with Medicaid can be a complex, multi-step process marked by delays and uncertainty, often resulting in long wait times, according to a new Weill Cornell Medicine study. Medicaid is a ...
2 hours ago
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Parkinson's symptoms trace to distinct brain circuits
Parkinson's disease is often treated as a single disorder. But for the more than 1.1 million people living with it in the United States, the disease can look different from one person to the next. Research from Carnegie Mellon ...
4 hours ago
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New genetic map of the human eye reveals clues to vision loss
An international team led by University of Manchester scientists has created the most detailed picture yet of how genetic differences shape the way the human eye works. The breakthrough could help explain why millions of ...
8 hours ago
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Whole organ 3D imaging reveals remaining insulin producing cells in type 1 diabetes
Researchers at Umeå University have conducted a unique three-dimensional mapping of an entire human pancreas. The study shows that insulin-producing cells can remain long after the onset of type 1 diabetes—a finding that ...
4 hours ago
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Inhaled fine particulate matter travels beyond the lungs to the brain, radiocarbon nanotracing reveals
Checking the fine particulate matter levels along with the weather every morning has become a daily routine. Research continues to show that fine particulate matter affects not only the respiratory system but also the brain ...
8 hours ago
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Memory decline after menopause linked to loss of estrogen production in brain tissue
A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.
11 hours ago
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Magnet-guided soft robots could lead to safer treatment of life-threatening blood clots
Researchers at Concordia have developed an AI-assisted technique and a robotic platform that may one day help surgeons perform safer, faster and less invasive procedures to treat conditions such as blood clots located deep ...
5 hours ago
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How 'Pac-Man' cells fail to prevent deadly infection risk in people with cystic fibrosis
Researchers have discovered how part of the body's immune system could better combat a leading cause of death for people with cystic fibrosis (CF). A team led by The University of Queensland's Professor Peter Sly and Dr. ...
8 hours ago
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Wearable ultrasound patch for high-risk pregnancies could improve care
Engineers at the University of California San Diego have created a soft, wearable ultrasound patch that can continuously monitor a fetus for hours at a time—and it can do so consistently even as the fetus and umbilical cord ...
12 hours ago
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Experimental gene therapy can shield brain from toxic protein damage
A new study led by researchers at the University of California San Diego School of Medicine suggests that an experimental gene therapy could help protect the brain from the damage and cognitive decline linked to TDP-43-related ...
4 hours ago
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Blood test detects early signs of breast cancer recurrence
Researchers at Lund University have developed a blood test capable of detecting signs of breast cancer recurrence long before recurrence becomes visible on imaging or causes symptoms. It has previously been shown that this ...
5 hours ago
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Rare 'burrowing' oral cancer shows distinct genetic profile for early diagnosis
Cancer diagnosis can be challenging, and delayed diagnosis can allow cancer to progress, complicating treatment. Oral squamous cell carcinoma (OSCC), the most common type of oral cancer, can sometimes mimic benign conditions, ...
9 hours ago
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RSV mutations tied to severe childhood cases uncovered after 2022 surge
Respiratory Syncytial Virus (RSV) is a common childhood disease. Most people catch and recover from it by the age of three. 2022 was different, though. There was a severe and early outbreak of RSV that overwhelmed hospitals.
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