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Vitamin D analog shuts down pancreatic cancer's shield in a clinical trial

A small clinical trial led by Dana-Farber Cancer Institute researchers has put a Salk Institute idea to the test in patients: that activating the vitamin D receptor can help reshape the protective environment surrounding ...

Hidden brain circuit could explain how movement errors sharpen new skills

While humans are acquiring new skills that entail performing coordinated movements, such as walking, playing an instrument or skateboarding, their brains are known to continuously detect mistakes and correct movements over ...

Medical research news

Parkinson's symptoms trace to distinct brain circuits

Parkinson's disease is often treated as a single disorder. But for the more than 1.1 million people living with it in the United States, the disease can look different from one person to the next. Research from Carnegie Mellon ...

New genetic map of the human eye reveals clues to vision loss

An international team led by University of Manchester scientists has created the most detailed picture yet of how genetic differences shape the way the human eye works. The breakthrough could help explain why millions of ...

Blood test detects early signs of breast cancer recurrence

Researchers at Lund University have developed a blood test capable of detecting signs of breast cancer recurrence long before recurrence becomes visible on imaging or causes symptoms. It has previously been shown that this ...

Specialized RNA molecules could counter ALS neurodegeneration

Misshapen proteins cause a mess of trouble—particularly in neurodegenerative diseases. But a new study suggests it's possible that giving them a little bit of extra support could keep them working correctly, and even reverse ...

Metformin's real power may be in the gut

For decades, physicians and scientists thought metformin, the leading type 2 diabetes medication taken by millions worldwide, mainly targets the liver to suppress glucose production. But a new Northwestern University study ...

Brain imaging reveals migraine headache subtypes

They've been described as "brain on fire" or "an ice pick through the head." Migraine headaches affect more than one in 10 Americans, and they're so much worse than a regular headache.