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Common arthritis pill repurposed to boost hair regrowth in alopecia patients

Upadacitinib is a medication widely used for the treatment of rheumatoid arthritis that works by inhibiting Janus kinase (JAK) enzymes, which are involved in signaling pathways that regulate immune responses. Now, scientists ...

Experimental pill targets nerve pain pathway, cutting opioid use after abdominal surgery

Opioids can be highly effective at relieving moderate to severe pain, whether it comes from surgery, an injury or conditions such as cancer. They work by activating opioid receptors in the brain and body, which block pain ...

Medical research news

Laser therapy offers weapon against deadly brain tumors

For patients facing a diagnosis of glioblastoma—one of the most aggressive and devastating forms of brain cancer—the standard path forward has long meant invasive open-skull surgery and a daunting prognosis.

Flexible brain circuits can switch between different tasks

As we move through everyday life, our brains engage in a huge variety of cognitive tasks. For example, during a grocery run, we might have to recall the items for a recipe, remember where the clerk said the flour was located ...

Rare gene variants may multiply Alzheimer's disease risk

Alzheimer's disease is the most common form of dementia worldwide, and its development is influenced by a combination of genetic and environmental factors. In recent years, the PLCG2 gene and its encoded enzyme, PLCγ2, have ...

Video games built for prevention can reduce teen depression

Few parents or teachers are likely to suggest that teenagers could benefit from playing more video games. But a new study suggests that a growing class of educational games may be a highly effective tool for treating and ...

Arthritis origins may begin before birth

Researchers at the Kennedy Institute have discovered that some joints may be more susceptible to inflammatory arthritis before birth, offering new insight into why rheumatoid arthritis attacks particular joints while sparing ...

Taking the stairs could cut risk of early death

Taking the stairs could help you live longer—according to new research from the University of East Anglia and the Norfolk and Norwich University Hospital. The study, published today, suggests that climbing stairs significantly ...

How brain ripples help support working memory

Research from scientists at the University of California San Diego School of Medicine and collaborators has shed new light on how the human brain coordinates working memory, the process in which the brain encodes information ...

For the tiniest patients, new tech brings clearer MRI images

Some of medicine's smallest patients can present its biggest imaging challenges. An infant's heart can be as small as a walnut, beating rapidly inside a body that will change dramatically as the child grows. Yet much of the ...