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Air pollution and mortality: Global study reveals persistent health risks despite declining pollutant levels

Even when air pollutant concentrations decrease, the health risks posed by these pollutants can remain consistently high. This is the conclusion of an international study conducted under the leadership of researchers from ...

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Novel biomarker could lead to early diagnosis of Alzheimer's disease, pilot study suggests

New research has discovered a unique and promising avenue for diagnosing Alzheimer's disease (AD) earlier—by analyzing AD biomarkers in blood—so that the impacts of dementia can be reduced.

Medical research

Newly discovered gene may influence longevity in humans

Sleep, fasting, exercise, green porridge, black coffee, a healthy social life—there is an abundance of advice out there on how to live a good, long life. Researchers are working hard to determine why some people live longer ...

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New approach moves cell therapy closer to treating many disorders

A new approach to manufacturing cells that secrete and deliver therapies to specific parts of the body has taken a big step toward one day repairing joints and damage after heart attacks, countering transplant rejection and ...

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Blood stem cell research could transform bone marrow transplants

Melbourne researchers have made a world first breakthrough in creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia ...

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Ultrasound device shows promise for treating chronic pain

Pain is a necessary biological signal, but a variety of conditions can cause those signals to go awry. For people with chronic pain, the root is often faulty signals emerging deep within the brain, giving false alarms about ...

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How cells keep gene silencing in check

Long considered 'junk," non-coding RNAs have emerged as important regulators of diverse cellular processes, including the silencing of genes. Working in yeast, researchers from the Bühler group have identified more than ...

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Remarkable new insights into the pathology of Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses. For some 25 years ...

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Can you tell if you're hitting the right note?

Anyone who likes to sing in the shower probably knows that they sometimes sing out of tune. But what about professional singers? How well do they evaluate their own abilities? And what role does this self-assessment play ...

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Using mice to explore the prevention of blocked arteries

It's long been known that a high-fat diet can lead to clogged arteries, but we have only recently begun to learn in detail how the process works. A new study in experimental mice could go a long way to finding treatments ...

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Can leukemia in children with Down syndrome be prevented?

For the first time, Princess Margaret researchers have mapped out where and how leukemia begins and develops in infants with Down syndrome in preclinical models, paving the way to potentially prevent this cancer in the future.

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Genetic factors linked to response to common antiviral medications

St. Jude Children's Research Hospital scientists and collaborators in Sweden and Japan are reporting that the enzyme NUDT15 plays a role in how patients respond to antiviral therapy with the common drugs ganciclovir and acyclovir. ...

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Scientists find liver drug candidates among pesticides

Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for ...

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A nuclear gatekeeper that regulates bone formation

Important insights into the cellular processes underlying healthy bone formation and development have been gleaned by a RIKEN-led study into a previously unknown bone disorder1.

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Mucus and mucins may become the medicine of the future

Many people instinctively associate mucus with something disgusting, but in fact, it has incredibly many valuable functions for our health. It keeps track of our important intestinal flora and feeds the bacteria. It covers ...

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Muscles retain positional memory from fetal life

A research collaboration based in Kumamoto University, Japan has discovered that muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body. This ...

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Missing bile ducts offer clues to mechanism of liver injury

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice. But despite ...