Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer's disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. ...
Feb 25, 2016
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A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.
Nov 16, 2015
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It is a hallmark of Alzheimer's disease: Toxic protein fragments known as amyloid-β clumped together between neurons in a person's brain. Neurons themselves make amyloid-β, and for reasons that aren't fully understood, ...
Aug 18, 2015
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Much like the automatic focus of a camera, our eyes and brains must constantly recalibrate so that we can get a clear view of the changing—and always moving—world around us. Recently, two studies funded by the National ...
Jun 3, 2015
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Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute have identified the molecular "glue" that builds the brain connections that keep visual images clear and still, even as objects ...
May 7, 2015
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An innovative laboratory culture system has succeeded, for the first time, in reproducing the full course of events underlying the development of Alzheimer's disease. Using the system they developed, investigators from the ...
Oct 12, 2014
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A research team led by the National Neuroscience Institute (NNI) has uncovered a novel function of the Amyloid Precursor Protein (APP), one of the main pathogenic culprits of Alzheimer's disease. This discovery may help researchers ...
Apr 21, 2014
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A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called ...
Apr 20, 2014
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In a study published today in Nature Neuroscience, a group of researchers led by Takaomi Saido of the RIKEN Brain Science Institute in Japan have reported the creation of two new mouse models of Alzheimer's disease that may ...
Apr 13, 2014
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New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer's Disease (FAD), a genetic variant of the disease that affects a small fraction ...
Jan 10, 2014
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