Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and robust gene reconstitution ...
Feb 3, 2026
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The DGIST Center for Synapse Diversity and Specificity has identified MDGA2 as a novel causative gene for developmental and epileptic encephalopathy (DEE), a rare and intractable neurological disorder occurring in infancy ...
Feb 3, 2026
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"By cleverly combining new techniques for analyzing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia," predicts Professor John van Noort. Together with ...
Feb 3, 2026
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Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have identified a mechanism that protects the female brain from genetic diseases. Although one of the two X chromosomes is switched off in female cells ...
Feb 2, 2026
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Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, which helps regulate ...
Feb 2, 2026
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Despite major advances in genetic testing for breast cancer risk prediction, death rates remain disproportionately high among women of African ancestry. This is often due to a combination of factors, including failure of ...
Feb 2, 2026
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Congenital stationary night blindness (CSNB) is caused by mutations in a specific calcium channel. A comprehensive proteomic study by researchers at the University of Innsbruck now reveals how these mutations trigger complex, ...
Feb 2, 2026
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In order for heart and vascular cells to develop properly and remain healthy for a long time, many processes in the cells must interact precisely. A new study from the German Center for Cardiovascular Research (DZHK) now ...
Feb 2, 2026
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Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease, affecting more than 10 million people worldwide. People with this condition may experience tremors, limb stiffness, gait ...
Feb 2, 2026
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How much do your genes determine how long you'll live? It's a question that fascinates us, and one that's been debated for decades. For years, the answer seemed settled—genes account for about 20–25% of the variation in human ...
Feb 2, 2026
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