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Immunology news

Oncology & Cancer

Study finds estrogens play a hidden role in cancers, inhibiting a key immune cell

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast ...

Immunology

Research reveals mechanism of effector-triggered immunity

A pair of studies examining immune response in C. elegans reveal broad implications for understanding pathogen detection in higher animals and the evolutionary origins of immunity itself.

Immunology

Circadian rhythm disruption linked to lung inflammation

In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption ...

HIV & AIDS

'Undetectable' HIV patients could hold key to treatments

A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert.

Immunology

Novel antibodies against Klebsiella pneumoniae identified

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections. Using genetic and functional approaches, the researchers also managed ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Diseases, Conditions, Syndromes

An eye on viruses in wastewater: Q&A with virologist

Virologist Rúbens Alves, Ph.D., came to La Jolla Institute for Immunology (LJI) to contribute to life-saving vaccine research. As a member of LJI's Shresta Lab, Alves studied how T cells fight viruses such as SARS-CoV-2 ...

Immunology

Researchers discover new role of immune cells in eye health

The eye is an immune-privileged tissue because of the need to keep blood vessels away from the central pathway of light and to restrict entry of inflammatory cells that could cause damage. This has prompted questions about ...

Oncology & Cancer

B-cells hold promise for treating glioblastoma

Harnessing the body's B-cells to fight tumors may be a promising treatment for glioblastoma, according to a Northwestern Medicine study recently published in the Journal of Clinical Investigation.

Oncology & Cancer

Researchers identify patterns that predict ovarian cancer relapse

Using spatial analysis of tissue samples, Cedars-Sinai investigators have identified patterns that could predict whether patients with the most common type of ovarian cancer will experience early relapse after treatment. ...

Immunology

FDA adds Fasenra indication for severe asthma in children

The U.S. Food and Drug Administration has approved an additional indication for AstraZeneca's Fasenra (benralizumab) as an add-on maintenance treatment for patients aged 6 to 11 years with severe asthma and an eosinophilic ...

Oncology & Cancer

Antibiotics reveal a new way to fight cancer

Cancer cells grow and spread by hiding from the body's immune system. Immunotherapy allows the immune system to find and attack hidden cancer cells, helping cancer patients live longer lives. However, many patients get little ...

Diseases, Conditions, Syndromes

Specific nasal cells found to protect against COVID-19 in children

Important differences in how the nasal cells of young and elderly people respond to the SARS-CoV-2 virus, could explain why children typically experience milder COVID-19 symptoms, finds a new study led by researchers at UCL ...

Medications

Penicillin allergy can be delabeled by nonallergy providers

Direct oral penicillin challenges (DPCs) can be delivered to patients with penicillin allergy labels (PALs) by nonallergy health care professionals (HCPs), according to a study published in the March issue of the Journal ...