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Immunology news

Oncology & Cancer

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

A Cleveland Clinic-led research collaboration between Timothy Chan, MD, Ph.D., Chair of Cleveland Clinic's Global Center for Immunotherapy, and Bristol Myers Squibb has published the most comprehensive overview to date of ...

Diseases, Conditions, Syndromes

New mouse models offer valuable window into COVID-19 infection

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.

Oncology & Cancer

Blood cancers: Expert explains what you need to know

Blood cancer is not a diagnosis anyone wants to receive, but understanding the different types of this disease and how best to catch them early is essential, one expert says.

Oncology & Cancer

What is CAR-T cell therapy? Oncologist explains

Roughly 635,000 new cases of lymphoma were diagnosed worldwide, according to the World Cancer Research Fund International's most recent report. Survival rates for aggressive lymphomas have improved significantly thanks to ...

Immunology

Circadian rhythm disruption linked to lung inflammation

In a study published in the journal Frontiers in Immunology, researchers at the University of Arizona Health Sciences Center for Sleep, Circadian and Neuroscience research have explored the effects of circadian rhythm disruption ...

HIV & AIDS

'Undetectable' HIV patients could hold key to treatments

A rare group of HIV-positive people who maintain undetectable levels of the virus in their blood without medication could hold the key to new therapies for others living with the disease, says a leading genome expert.

Immunology

Novel antibodies against Klebsiella pneumoniae identified

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections. Using genetic and functional approaches, the researchers also managed ...

Oncology & Cancer

The complex role of pyroptosis in lung cancer

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor prognosis in its advanced stages.

Immunology

COVID-19 vaccines produce antibody response in the nasal mucosa

Respiratory viruses are known for their ability to enter the body through the eyes, nose, or mouth. Our bodies know that too. The nasal cavity is well-equipped with sticky mucus that traps pathogens and serves as an important ...

Immunology

Tuning T cell traits and functions with biomechanical materials

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against ...

Oncology & Cancer

Researchers discover a new mechanism of cancer immune defense

An interdisciplinary team of researchers at the Otto-von-Guericke University in Magdeburg has gained new insights into how inflammatory mediators of pathogen defense can remotely drive cancer cells into death—an important ...

Oncology & Cancer

How popular steroids could interfere with some cancer treatments

Immunotherapy is among the newest and most potent weapons against cancer. It prompts the immune system to recognize tumors as intruders in the body and attack. But not all patients respond well to immunotherapy. Why? Scientists ...