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Immunology news
Oncology & Cancer
New research shows how Golgi stress affects T-cells' tumor-fighting ability
The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the setting of cancer immunology, ...
12 hours ago
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Oncology & Cancer
Clinical trial: Monoclonal antibody may be an effective alternative to cisplatin in treatment of head and neck cancers
Head and neck cancers are the seventh most common type of cancer worldwide, according to the 2020 World Cancer Report. Smokers and drinkers, as well as those with HPV infections, are disproportionately affected.
16 hours ago
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Study reveals how glioblastoma evades treatment; identifies potential new treatment strategy
A new study from scientists at the UCLA Health Jonsson Comprehensive Cancer Center helps explain why glioblastoma, one of the most aggressive forms of brain cancer, becomes resistant to treatment, and introduces a new approach ...
Nov 21, 2024
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Signals of inflammation during pregnancy linked to aging and memory changes 50 years later
An estimated 13.8 million people in the U.S. will have Alzheimer's disease (AD) by 2050, two thirds of whom are projected to be women. The brain circuitry underlying memory is widely known to differ based on biological sex, ...
Nov 21, 2024
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Researchers discover new combination therapy approach for metastatic ovarian cancer
The Wistar Institute's Nan Zhang, Ph.D., assistant professor in the Ellen and Ronald Caplan Cancer Center's Molecular and Cellular Oncogenesis Program, and colleagues have discovered a new approach to treating ovarian cancer, ...
Nov 21, 2024
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New thesis on MAIT cells provides insights into immunity and COVID-19
Tobias Kammann from the Center for Infectious Medicine (CIM) at the Department of Medicine, Huddinge (MedH) is defending his thesis titled "The diversity of MAIT cells across the human body and in COVID-19," on 29 November, ...
Nov 21, 2024
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The health benefits of fright: A haunted house study
Aarhus University, Denmark, researchers suggest that recreational fear experiences, such as haunted house attractions, may reduce inflammation in individuals with low-grade inflammation.
Scientists find a region of mouse gut tightly regulated by the immune system
The intestine maintains a delicate balance in the body, absorbing nutrients and water while maintaining a healthy relationship with the gut microbiome, but this equilibrium is disrupted in parts of the intestine in conditions ...
Nov 20, 2024
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Probiotic delivers immunotherapy to shrink gut tumors in mice
Immunotherapy is a promising treatment that recruits the immune system to help fight cancer, but it has had limited success in gastrointestinal cancers. Now, researchers at Washington University School of Medicine in St. ...
Nov 20, 2024
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Protein disruption reveals potential treatment option for people with debilitating skin condition
Hidradenitis suppurativa, commonly referred to as HS, is a debilitating skin condition that causes chronic inflammation on the surface of the skin. This condition is characterized by painful bumps or boils that form under ...
Nov 20, 2024
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Preventing severe malaria by harnessing natural human antibodies
Malaria, particularly in its severe forms, remains a global health and economic burden. It causes the deaths of more than 600,000 people every year—most of them African children under five.
Nov 20, 2024
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Map of human thymus sheds light on how immune responses are built and maintained at early life
By creating the first spatial atlas of the developing human thymus, a vital organ that trains immune cells to protect against infections and cancer, scientists have discovered that the foundation for lifelong immunity is ...
Nov 20, 2024
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Microscopic, single-cell differences found in the lungs of COVID-19 patients in Malawi
Microscopic, single-cell differences found in the lungs of COVID-19 patients in Malawi demonstrate the value and importance of cutting-edge infectious disease research in Sub-Saharan Africa.
Nov 20, 2024
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Bayesian metamodeling provides insight into how T cells are activated
A research team behind a new study at the Hebrew University of Jerusalem has made an important breakthrough in understanding how immune cells known as T cells are activated.
Nov 20, 2024
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Experimental therapeutic reduces advanced-stage influenza viral loads faster than current therapies in preclinical study
Eradivir, a preclinical biotech company, has developed a patent-pending antiviral therapeutic that reduces lung viral loads of advanced-stage influenza in preclinical studies quicker and more effectively than currently available ...
Nov 19, 2024
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Salmonella research unlocks the potential of bacteria to treat bowel cancer
Fighting bowel cancer with the bacteria Salmonella could be a step closer thanks to a new discovery by researchers at the University of Glasgow and the University of Birmingham.
Nov 19, 2024
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Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies
A study at MedUni Vienna's Department of Dermatology provides insights into the diversity of cancer-associated fibroblasts in skin cancer and describes their different immunomodulatory roles in the tumor environment. The ...
Nov 19, 2024
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Surprising connection between COVID-19 and cancer regression
A new study led by scientists from the Northwestern Medicine Canning Thoracic Institute and published in the Journal of Clinical Investigation has revealed a connection between COVID-19 infection and cancer regression. The ...
Nov 19, 2024
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Immunotherapy shows potential to treat deadly thyroid cancer
A type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results of a clinical trial published in JAMA Oncology.
Nov 19, 2024
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Developing an antibody to combat age-related muscle atrophy
We all age. And while humanity's life expectancy has increased dramatically in the modern era, we still struggle with the inevitable health issues our bodies face as we get up in the years. For example, the decrease of muscle ...
Nov 19, 2024
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New insights reveal how house dust mites trigger allergic asthma by activating immune system
New research from the University of Pittsburgh uncovers how inhaled house dust mites, a common trigger of allergic asthma, activate the immune system and drive this disease in mice.
Nov 18, 2024
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T-cell dysfunction increases cancer risk in obese populations, researchers say
Researchers at Saint Louis University's School of Medicine say T-cell dysfunction is leading to an increased risk of cancer in obese populations.
Nov 18, 2024
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Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors
One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast cancer with a poorer prognosis. Investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Growth ...
Nov 18, 2024
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AI analysis of immune cells can predict breast cancer prognosis
Researchers at Karolinska Institutet have investigated how well different AI models can predict the prognosis of triple-negative breast cancer by analyzing certain immune cells inside the tumor. The study, published in the ...
Nov 18, 2024
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Q&A: Thesis sheds light on the role of immune molecules in severe bacterial infections
Helena Alpkvist from the Infectious Diseases and Dermatology Unit at the Department of Medicine, Huddinge, is defending her thesis titled "Damage-associated molecular patterns and pathogen-associated molecular patterns in ...
Nov 18, 2024
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