Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune-based therapies). Despite harboring the highest tumor mutational burden of all cancers, basal cell ...
3 hours ago
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A team of researchers from the University of Chicago, in collaboration with researchers from the University of Pittsburgh, has identified a novel oncometabolite that accumulates in tumors and impairs immune cells' ability ...
16 hours ago
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Tuberculosis (TB) is an infectious disease that kills more than a million people worldwide every year. The pathogen that causes the disease, Mycobacterium tuberculosis, is deadly in part because of its complex outer envelope, ...
17 hours ago
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A subset of patients with non-small cell lung cancer (NSCLC) who discontinued immune checkpoint inhibitor (ICI) therapy due to immune-related adverse events (irAEs) continued to experience long-term disease control, according ...
16 hours ago
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Chris Vogelsang has had a long and terrible fight with cancer.
22 hours ago
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Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center ...
Apr 21, 2025
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When the immune system does not function properly, individuals become more susceptible to infections caused by viruses, bacteria, or fungi. Researchers from Radboud University Medical Center have demonstrated that an existing ...
Apr 18, 2025
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A newly developed radiolabeled antibody that targets the cancer antigen IL13Rα2 has been found to be highly specific, binding only to cancer cells and not to the related antigen IL13Rα1, which is widely expressed in healthy ...
Apr 18, 2025
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Spring has sprung, and the battle with seasonal allergies is underway in earnest.
Apr 18, 2025
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High-intensity electrical pulses have been medically used to destroy tumors while sparing healthy tissue. But lower-intensity pulses may have a different effect—they reshape the battlefield, making tumors more vulnerable ...
Apr 17, 2025
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